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Protein Alignment CG7025 and CPA1

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens

Alignment Length:	431	Identity:	161/431 - (37%)
Similarity:	245/431 - (56%)	Gaps:	46/431 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRL--WHEAKDELHLM 71
            :|.|.||. ||.||:::   :..:.|.::....:||...:::| ||.|:.:|  |   :...|
Human     4 LLVLSVLL-GAVFGKED---FVGHQVLRISVADEAQVQKVKEL-EDLEHLQLDFW---RGPAH-- 58

  Fly    72 LSPGA-------FGELETE---IQKTNVTAELFISNVQELIDSEE----AANLKASRDGTFGWTK 122
              ||:       |..::..   ::...::.|..|.:||.|:|.|:    |...:|....||.:..
Human    59 --PGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYAT 121

  Fly   123 YNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISY-KSNNPGVLIESNIHAREWITS 186
            |::|.|||.:||.::|..|.:.....:|.:||||.|..:|.|. .|..|.:.|::.||:|||:|.
Human   122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQ 186

  Fly   187 ATATWLINEFLTSTDELVRDLA-----ENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSC 246
            |:..|...:.   |.:..:|.|     :..|.::..|.|.|||.:||..:|||||||..:..|.|
Human   187 ASGVWFAKKI---TQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLC 248

  Fly   247 IGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKD--KINVLLAFHSYS 309
            ||.|||||:|:.: ...|||||||:|.|.|....||.|::::.:||   ||  .|...::.||||
Human   249 IGVDPNRNWDAGF-GLSGASSNPCSETYHGKFANSEVEVKSIVDFV---KDHGNIKAFISIHSYS 309

  Fly   310 QLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQ 374
            |||:.|||: |.|..|:.|::.:::||...|:.|| |||.:.|||....:|.|||:||||.|: |
Human   310 QLLMYPYGY-KTEPVPDQDELDQLSKAAVTALASL-YGTKFNYGSIIKAIYQASGSTIDWTYS-Q 371

  Fly   375 GVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLE 415
            |::.|:|.|.||||||||:||...|||.|:|..:.:..::|
Human   372 GIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIME 412

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.