DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and cpa3

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_031758725.1	Gene:	cpa3 / 100494117	XenbaseID:	XB-GENE-853724	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	427	Identity:	137/427 - (32%)
Similarity:	229/427 - (53%)	Gaps:	46/427 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRL--WH----------- 62
            |..|||:....|.         .|::.|.:|:...:::.|:   :|..:|  ||
Frog    17 ASAVLAKQTFHGD---------KVFRAKLQTEGHVALIHKI---KEAIKLDFWHPDTADRMVPHT 69

  Fly    63 EAKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLA 127
            ||...:|   |..| ..::..:|:.:|..|:...::||.|:::.....|:.|   ..:||||:..
Frog    70 EADFHVH---SDQA-DSVQILLQQNSVPYEVLFHDLQEGIEAQLNNTKKSKR---HSYTKYNTWE 127

  Fly   128 EIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNP-----GVLIESNIHAREWITSA 187
            :|..|...:...||.:.:...:|:|.|||.:..:::    .||     .:.::..|||||||:.|
Frog   128 KIVEWTSKLTKKYPNLVQRIDIGKSVEGRPMYVLQV----GNPDSATKAIFMDCGIHAREWISPA 188

  Fly   188 TATWLINEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPN 252
            ...|.:.|.:...:. :|:|.::..:||:||.|:||:|:|..:||||||.|.|||.:.|:|.|.|
Frog   189 FCQWFVKELIKGKNN-IRELVKSLTFYILPVFNIDGYVWTWTEDRMWRKNRSPSEDAKCVGTDLN 252

  Fly   253 RNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYG 317
            ||::..|.: .|:|..||:|.|.|....||.|.:.::.|:.|..|.|...::|||:||:||.|:.
Frog   253 RNFNISWCD-IGSSDEPCSEIYCGAAAESEIETKNVASFIRSHVDSIKAYISFHSFSQMLLFPFS 316

  Fly   318 HTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTI 382
            :| .|..|:..::.|:||.....::.| |||.|.||.:|..:||.:|::.||||: .|::.|:|.
Frog   317 YT-YELAPDHKELDEIAKGAVAELQGL-YGTSYTYGPSASTIYPTAGSSDDWAYS-LGIKYSFTF 378

  Fly   383 EFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKD 419
            |.||.|:.||:||...|....:|..:.:|.:.:...|
Frog   379 ELRDEGKKGFLLPQSQIKATCQETTLAVAYIAKYVLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	17/79 (22%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	108/297 (36%)
cpa3	XP_031758725.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920