DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and cpo

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	313	Identity:	120/313 - (38%)
Similarity:	185/313 - (59%)	Gaps:	11/313 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 TFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNP--GVLIESNIH 179
            ::.:|||:::.||.||::.:....|.:..:...||:||.|.|..:||.:.|..|  .:.::..||
Zfish    29 SYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTTPKKAIWMDCGIH 93

  Fly   180 AREWITSATATWLINEFLTS--TDELVRDLAENHDWYIVPVLNVDGFVYT--HEKDRMWRKTRQP 240
            |||||..|.....:.|.|.|  ||..|..|.:|.|:||.||||:||::|:  :...|:|||:|.|
Zfish    94 AREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSP 158

  Fly   241 -SEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLA 304
             .|.|:|.|.|.|||:.::| ...|.|.|.|:|.|.|....||||.:|:::|:.:.::.:...|.
Zfish   159 CHENSTCSGTDLNRNFYANW-GMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLT 222

  Fly   305 FHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDW 369
            .|||.||:|.||||.... .||:|::|||..|...|:::: :|..|:.||:..:|||.||::.|:
Zfish   223 IHSYGQLILVPYGHPNIS-APNYDELMEVGLAAAKAIKAV-HGKSYKVGSSPDVLYPNSGSSRDF 285

  Fly   370 AYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGY 422
            | ...|:..|:|.|.||.|::|||||...|.|..:||..|..:::....|..:
Zfish   286 A-RLIGIPYSFTFELRDEGQHGFILPEDQIQPTCQEAYEGAMSIINYVHDKNF 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	117/299 (39%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	117/300 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593507
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.780