DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and cpb2

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001025617.1	Gene:	cpb2 / 595005	XenbaseID:	XB-GENE-969491	Length:	421	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	128/372 - (34%)
Similarity:	212/372 - (56%)	Gaps:	17/372 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IEKIGELTKKYNI--WK----EYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERID 104
            :|.:..:|.:..|  ||    |:..:::::...|:...::..:..|..::|...:::.|.||.|:
Frog    38 VEILKNITSQPEIVLWKPDSNEHIMKNKEVHFYVNESFIDTVKAELNESSILYMVLVNNAQELIE 102

  Fly   105 EEQVTPTAD--SATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKIS--HK 165
            ::....|::  |||..:.:|:.||:|..|:..::..:..:.:...:|.|:|.|.:..:|:|  .|
Frog   103 QQTFNDTSNQRSATSFYEQYHTLEDIYYWMQHMVEKHSDMLQRIHIGYSFENRPLYVLKVSGKEK 167

  Fly   166 AGNPGIFIESNIHAREWITSASATWFINQLLT--SEDADVRSLADNYDWHIIPVFNVDGFEYS-H 227
            .....::|:..|||||||:.|...||:...:.  ..|..:..|....|::|:||.|.||:::| .
Frog   168 TAKHAVWIDCGIHAREWISPAFCLWFVGHAVEYYGVDLSMTKLLRYLDFYILPVMNADGYQFSWT 232

  Fly   228 KKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLT 292
            .|:|||||.|..:..:.|||.|.|||||:.|. ..|||.:||.|.:.|...|||||..|:|.:|.
Frog   233 AKNRMWRKNRSKYTKSNCIGTDLNRNFDAGWC-GPGASSDPCHEIYCGPYAESEPEVSAVVSFLK 296

  Fly   293 KIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADV 357
            |.|:.:..||:.|||.|.:|.||.:||:: .::::::|.:.|..|:.|.:..... |.||:.|:.
Frog   297 KHQNVVKGYITVHSYSQMVLFPYSYTNKK-SKDHDELLLLSKKVAEGIRSTSRNK-YMYGAGAET 359

  Fly   358 LYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQIIPNCEE 404
            :|:|.|.|.||.: :||.|..:|.|.||||.|||:|||..|.|.|.|
Frog   360 IYLAPGGSDDWAY-DLGIKYSFTFELRDKGMYGFLLPPQLIKPTCSE 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	13/64 (20%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	111/288 (39%)
cpb2	NP_001025617.1	Propep_M14	33..104	CDD:366995	13/65 (20%)
cpb2	NP_001025617.1	M14_CPB2	118..418	CDD:349465	111/292 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.950