back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18585 and CPA6

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_065094.3	Gene:	CPA6 / 57094	HGNCID:	17245	Length:	437	Species:	Homo sapiens

Alignment Length:	428	Identity:	131/428 - (30%)
Similarity:	229/428 - (53%)	Gaps:	24/428 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWK----EYD 63
            |.||...::....:.:..:    ||...:|.:...:.:.:..|::|| ....|.::|:    .|.
Human    17 LCWLFLKILQPGHSHLYNN----RYAGDKVIRFIPKTEEEAYALKKI-SYQLKVDLWQPSSISYV 76

  Fly    64 ERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADS----ATFGWTKYYE 124
            ......|:.:...........|:..||..:::||::|:.:::.....|..:    :.:.:..|:.
Human    77 SEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHS 141

  Fly   125 LEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAG-NPGIFIESNIHAREWITSASA 188
            ||||:.|:..:...:..:...|.:|:|||||::..:|:..::. ...::|:..|||||||..|..
Human   142 LEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFC 206

  Fly   189 TWFINQLLTSEDAD--VRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADAN 251
            .||:.:.|.:..:|  :|.:.::..::|:|||||||:.:|...||.|||||..::...|.|.|||
Human   207 QWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDAN 271

  Fly   252 RNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYG 316
            ||:...|. :.|||.:||.:|:.|..||||||.||:..:|.|.:..|..|:|||:|.|.||.||.
Human   272 RNWKVKWC-DEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYS 335

  Fly   317 HTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTI 381
            :.....| |:..:.:......:|:::: ||..|:||..:..|||::|:|:||.:.. |....:..
Human   336 YKYATIP-NFRCVESAAYKAVNALQSV-YGVRYRYGPASTTLYVSSGSSMDWAYKN-GIPYAFAF 397

  Fly   382 EYRDKGRYGFILPPVQIIPNCEELMVGM----LALIEK 415
            |.||.|.:||:||.:.|.|.|.|.|:.:    :.|::|
Human   398 ELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKK 435

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.