DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and cpb1

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_031758320.1	Gene:	cpb1 / 496994	XenbaseID:	XB-GENE-853710	Length:	414	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	137/416 - (32%)
Similarity:	222/416 - (53%)	Gaps:	24/416 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIW----KEYDE 64
            :|.|..||:|.:.    .:....:...:|:::..||...:..|:.:.: |:..:.|    .:..|
Frog     1 MWALLLLVSLAAV----SAEPRNFHGEKVFRVIPQNAEHVELIKSMAQ-TEGLDFWLPDSAQLVE 60

  Fly    65 RSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADS---ATFGWTKYYELE 126
            :.::.|...........|.||:.:.:..|::|.::|:.:::::     ||   |...:.||.:|:
Frog    61 QGKRADFHADGHVSYEVQALLQQSGMPYEILINDLQDALEKQR-----DSNIRAVHSYEKYNDLD 120

  Fly   127 EIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGN-PGIFIESNIHAREWITSASATW 190
            .|.||...|....|.:.....:|.||:||.|..:|:.....| ..:||:...||||||:.|...|
Frog   121 TINAWSANIAAQNPGLVSRSSIGTSYQGRPIYLLKVGKSGANKKAVFIDCGFHAREWISPAFCQW 185

  Fly   191 FINQLLTS--EDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRN 253
            |:.:.:::  .:::..||.||.|.:::||.||||:.|:...:|||||||..:..:.|||.|.|||
Frog   186 FVKEAVSAYGVESEFTSLLDNLDIYVLPVLNVDGYVYTWTTNRMWRKTRSANPNSTCIGTDPNRN 250

  Fly   254 FDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHT 318
            |::.|. ..|||...|.||:.|..||||||.|||..::......|..|::.|||.|.||.||.:
Frog   251 FNAGWC-TAGASTRACDETYCGSAPESEPETKALANFIRANIPAIKGYLTIHSYSQMLLFPYSY- 313

  Fly   319 NEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEY 383
            :....:::|::..:.:...:::.:| |.|.|.||.....:|:|.|.|.||.: :.|.|..||.|.
Frog   314 SYAVAKDHNELNAVAQGAVNSLTSL-YKTKYTYGPGGSTIYLAAGGSDDWAY-DAGVKFSYTFEL 376

  Fly   384 RDKGRYGFILPPVQIIPNCEELMVGM 409
            ||.|||||.||..||.|.|||.|:.:
Frog   377 RDTGRYGFALPESQIKPTCEETMLAV 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	13/74 (18%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	114/291 (39%)
cpb1	XP_031758320.1	Propep_M14	31..102	CDD:396700	13/71 (18%)
cpb1	XP_031758320.1	M14_CPB	111..410	CDD:349443	115/296 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010