DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and CG4408

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	142/453 - (31%)
Similarity:	239/453 - (52%)	Gaps:	48/453 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WLLATLVALTSAGILK------------------------DSPKERYDNFRVYKLTIQNKIQLAA 45
            |||..||  :|..:::                        ||.:.|||:.|:|::.:.::..:..
  Fly    37 WLLLLLV--SSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHVRL 99

  Fly    46 IEKIGELTKKYNIWKEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEE--QV 108
            .:.:.:.:...:......:..:::.|||:..::..|.:|:...|::..::..|.|..||..  :|
  Fly   100 FQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEV 164

  Fly   109 TP-TADSATFGWTKYYELEEIEAWLDEILNAYPSV--TEEFIVGKSYEGRTIRGIKISHKAGN-P 169
            .| ......|.|.:|:.||.|.|||.::...:|.|  .|   :|.|.:||.|.|::|:....| .
  Fly   165 APEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVE---LGVSAQGRPILGVQIAFDNENRT 226

  Fly   170 GIFIESNIHAREWITSASATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWR 234
            .:|:||.|||||||..|:||:.|:||:.|:|:.|::||.:..|:|.|..|.||::|:.|.|||||
  Fly   227 TVFVESGIHAREWIAPATATYIIDQLVNSKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWR 291

  Fly   235 KTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLT-KIQ-DQ 297
            |.|.  ....|.|.|.||||..:| ...|||.:||...::|.:..||.|.:.::|::. ::: ::
  Fly   292 KNRA--LFGICRGVDLNRNFPFHW-NVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESER 353

  Fly   298 ISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVAT 362
            |..:||.|||.|.::.||||:.|.. :||:|:..|||..|:.|:.:. |.:|:.||..:.:|.::
  Fly   354 IRTFISLHSYSQMIMFPYGHSAERV-DNYHDLTDIGKLAANKIKDVS-GRIYKSGSIYETIYPSS 416

  Fly   363 GTSVDWVFNELGKKIGYTIEYRDKGRYG----FILPPVQIIPNCEELMVGMLALIEKTKELGY 421
            |.|.||...:|  ||..|..|..:|...    |||...:|.|...|....:..::::..:.||
  Fly   417 GGSKDWAHGQL--KIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQEAGKRGY 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	9/70 (13%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	113/301 (38%)
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	9/70 (13%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	113/302 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467020
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm4737
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800