DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and CG3108

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	142/414 - (34%)
Similarity:	219/414 - (52%)	Gaps:	51/414 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SAGILKDSPKE-----------------RYDNFRVYKLTIQ-NKIQLAAIEKIGELTKKYN--IW 59
            :|..::..|.|                 |||..:|:::.:| :|.:..|    .||..||:  :|
  Fly   694 NASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMA----DELQSKYDGQLW 754

  Fly    60 KEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSAT-------- 116
            ||.   .:::|.::.|..|...:..::..|:|..::|:|:|..|::|  .|.|:...
  Fly   755 KEV---KQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKE--NPPAEKIAELQNRKGH 814

  Fly   117 -FGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISH-KAGNPGIFIESNIHA 179
             ..|..|:.||:|..::|.:...||.:....|:|.|.|.|.::.:|||: .|.||||:|:..:||
  Fly   815 RLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHA 879

  Fly   180 REWITSASATWFINQLLTS-ED--ADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHA 241
            ||||:.|:.|:..|||:.. ||  ..:||:    :|:|.||.|.||:||||..||:|||..:.|.
  Fly   880 REWISPATVTYIANQLVEGWEDLPEHMRSI----NWYIHPVANPDGYEYSHTTDRLWRKNMRAHG 940

  Fly   242 TNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKI-QDQISVYISFH 305
             ..|.|.|.||||...| ...|.|.:|||:|:.|....||||...:.::::.. ::....|:|||
  Fly   941 -RQCPGVDLNRNFGYKW-GGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFH 1003

  Fly   306 SYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVF 370
            |||||:|.|:|: :.:..::..|:..:.:....:| ....|..|..||:|..||.|.|.|.||..
  Fly  1004 SYGQYILYPWGY-DYQLTQDRADLDRVARQAGTSI-TKSTGVKYTVGSSATTLYPAAGGSDDWAK 1066

  Fly   371 NELGKKIGYTIEYRDKGRYGFILP 394
            ...|.|..||||..|.|||||:||
  Fly  1067 GIAGIKYAYTIEMGDTGRYGFVLP 1090

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	19/73 (26%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	112/278 (40%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	19/73 (26%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	112/278 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466950
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	11	10.780