DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and CG3097

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	143/431 - (33%)
Similarity:	231/431 - (53%)	Gaps:	56/431 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLWLLATLVALTSAGILKDSPK-----------ERYDN---FRVYKLT--IQNKIQLAAIEKIGE 51
            :|..|..|||..:|.:..:.|.           :|||.   :|:|.::  :|.::.:..:
  Fly     6 MLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQM----- 65

  Fly    52 LTKKY--NIWKEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADS 114
            |.:|:  ||||   |.|:.:||.::..:|...:..|..:.:..:::..|:|..|||| :.....|
  Fly    66 LEQKFGGNIWK---ENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEE-LLEGIQS 126

  Fly   115 ATFG--------------WTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKIS-H 164
            ::||              |..|::||.|.:::.||...:|::...:.:|::.|||.::.::|| :
  Fly   127 SSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISEN 191

  Fly   165 KAGNPGIFIESNIHAREWITSASATWFINQLLT---SEDADVRSLADNYDWHIIPVFNVDGFEYS 226
            ...|..::|:..|||||||:.|:.|:.:.||::   ::.|.:|.|.    |:|:||.|.||:|||
  Fly   192 PRENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLT----WYIMPVMNPDGYEYS 252

  Fly   227 HKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYL 291
            ...:|:|||.|.|.....|.|.|.|||||..| ...|:|.||||:|:.|..|.||.|.:|:.|:|
  Fly   253 RTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGW-NGYGSSTNPCSDTYRGSAPASERETRAVAEFL 316

  Fly   292 TKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEAL--PYGTVYQYGST 354
            .|.:..:..|::||||||.::.|:.:.    .....|...:.:..:.|.|.:  ..||.|:...|
  Fly   317 AKRKYNLESYLTFHSYGQMIVYPWAYK----AVKVKDASVLQRVSSLAAERILQKTGTSYRAAVT 377

  Fly   355 ADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPP 395
            .:||.:|.|.|.||....||.|..||||.||:|.|||:|||
  Fly   378 HEVLGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	16/74 (22%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	108/280 (39%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	15/61 (25%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	108/280 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466954
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	10	9.900