DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and Agbl2

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_848870.2	Gene:	Agbl2 / 271813	MGIID:	2443254	Length:	862	Species:	Mus musculus

Alignment Length:	336	Identity:	61/336 - (18%)
Similarity:	122/336 - (36%)	Gaps:	111/336 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RYDNFR---VYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSRQIDIMV-SPGELNHFQELLK 86
            |..|.|   .|:.||.|.::..::..:|.....|:          |:|..: :.|.....:|:..
Mouse   271 RVQNTRKDATYRFTIVNLLKPKSLYAVGMKPLMYS----------QLDATIYNIGWRREGREIKY 325

  Fly    87 FNNISSELMIENVQERIDEEQ-----VTPTA------DSATFGWTKYYELEEIEAWLDEILNAYP 140
            :.|            .:|:.|     :|.|.      |:..|.....|...:::.:|..:.|  .
Mouse   326 YKN------------NVDDGQQPLYCLTWTTQFPHDQDTCFFAHFYPYTYTDLQCYLLSVAN--N 376

  Fly   141 SVTEEF----IVGKSYEGRTIRGIKISHKAGNP-------GIFIESNIHAREWITSASATWFIN- 193
            .:..:|    .:.:|..|.|:..:.|::.:..|       .:.:.:.:|..|    ::::|.:|
Mouse   377 PIQSQFCKLRALCRSLAGNTVYLLTITNPSRTPQEAAAKKAVVLSARVHPGE----SNSSWIMNG 437

  Fly   194 --QLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNF-- 254
              ..:.|...|.:.|.|.:.:.:||:.|.||....:.:..:             .|.|.||::
Mouse   438 FLDFILSNSPDAQLLRDIFVFKVIPMLNPDGVIVGNYRCSL-------------AGRDLNRHYKT 489

  Fly   255 ---DSY---WLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQ---- 309
               ||:   |...|                    ..|.|:|     :.::.:|..||.:.:
Mouse   490 VLKDSFPCIWYTKN--------------------MIKRLLE-----EREVLLYCDFHGHSRKNNI 529

  Fly   310 YLLSPYG-HTN 319
            :|   || |:|
Mouse   530 FL---YGCHSN 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	10/71 (14%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	41/225 (18%)
Agbl2	NP_848870.2	Pepdidase_M14_N	231..358	CDD:375499	20/108 (19%)
		M14_AGBL2-3_like	379..629	CDD:349478	38/204 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	669..692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..728
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	750..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900