DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	329	Identity:	96/329 - (29%)
Similarity:	159/329 - (48%)	Gaps:	30/329 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 FGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPG-----IFIESN 176
            |..|.|.:..:.|.::..:.:..||..:...:|::.|||.:.|::|. |...||     ::::..
Worm    30 FDLTVYNDWPQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRIG-KPALPGKRKIAVWLDGG 93

  Fly   177 IHAREWITSASATWFINQLLTS--EDADVRSLADNYDWHIIPVFNVDGFEYSHKKD----RMWRK 235
            .|||||.....|.:||.:|:..  .|..:....:..|.::.||.|.|||.||....    |.|||
Worm    94 NHAREWPAFHVAVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRAMIRQWRK 158

  Fly   236 TRQPHATN---------ACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYL 291
            .|.|....         .|.|.|.|||:|..:...|...:||||:.|.|..|.||||.:|:.:::
Worm   159 NRAPENCTGTGPFQTDICCEGVDLNRNYDIGFSHKNYPFNNPCSDEFQGPRPFSEPETRAVRDFI 223

  Fly   292 --TKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGST 354
              ::|..::...:|.|::||..:.||.:....:|::..|:..:....||.:.|. ..|.|:.|:.
Worm   224 MSSEIYGRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLEILANRAADRVFAY-RETKYRVGTA 287

  Fly   355 ADVLYVATGTSVDWVFNELGKKIGYTIEYRD--KGRYGFILPPVQIIPNCEELMVGMLAL----I 413
            ||:|..|||.:.||:......|..|.:|...  |..:.|.:.|..:||..:|..:|:..:    :
Worm   288 ADMLGTATGGATDWIKKNTPTKYVYVLELPPDMKTWFAFQVKPHWLIPIGKETWLGIEVIFDQVV 352

  Fly   414 EKTK 417
            |:||
Worm   353 EETK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	91/320 (28%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	89/303 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37541
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730