DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and cpa3

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	XP_031758725.1	Gene:	cpa3 / 100494117	XenbaseID:	XB-GENE-853724	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	147/421 - (34%)
Similarity:	230/421 - (54%)	Gaps:	31/421 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSR 67
            |:|:|.:..:...|       |:.:...:|::..:|.:..:|.|.||.|.. |.:.|.. |...|
Frog     9 LIWVLGSAASAVLA-------KQTFHGDKVFRAKLQTEGHVALIHKIKEAI-KLDFWHP-DTADR 64

  Fly    68 QI-----DIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGWTKYYELEE 127
            .:     |..|...:.:..|.||:.|::..|::..::||.| |.|:..|..|....:|||...|:
Frog    65 MVPHTEADFHVHSDQADSVQILLQQNSVPYEVLFHDLQEGI-EAQLNNTKKSKRHSYTKYNTWEK 128

  Fly   128 IEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNP-----GIFIESNIHAREWITSAS 187
            |..|..::...||::.:...:|||.|||.:..:::    |||     .||::..|||||||:.|.
Frog   129 IVEWTSKLTKKYPNLVQRIDIGKSVEGRPMYVLQV----GNPDSATKAIFMDCGIHAREWISPAF 189

  Fly   188 ATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANR 252
            ..||:.:|:..:: ::|.|..:..::|:||||:||:.::..:||||||.|.|.....|:|.|.||
Frog   190 CQWFVKELIKGKN-NIRELVKSLTFYILPVFNIDGYVWTWTEDRMWRKNRSPSEDAKCVGTDLNR 253

  Fly   253 NFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGH 317
            ||:..|. :.|:||.||||.:.|...|||.|.|.:..::....|.|..||||||:.|.||.|:.:
Frog   254 NFNISWC-DIGSSDEPCSEIYCGAAAESEIETKNVASFIRSHVDSIKAYISFHSFSQMLLFPFSY 317

  Fly   318 TNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIE 382
            |.|..|: :.::..|.|.....::.| |||.|.||.:|..:|...|:|.||.:: ||.|..:|.|
Frog   318 TYELAPD-HKELDEIAKGAVAELQGL-YGTSYTYGPSASTIYPTAGSSDDWAYS-LGIKYSFTFE 379

  Fly   383 YRDKGRYGFILPPVQIIPNCEE--LMVGMLA 411
            .||:|:.||:||..||...|:|  |.|..:|
Frog   380 LRDEGKKGFLLPQSQIKATCQETTLAVAYIA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	20/75 (27%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	115/297 (39%)
cpa3	XP_031758725.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920