DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and cpo

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	332	Identity:	125/332 - (37%)
Similarity:	198/332 - (59%)	Gaps:	14/332 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NISSELMIENVQERIDEEQVTPTADSATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYE 153
            :|:|.|::..:   :.::::....:..::.:|||:.::||.||::::....|.|......|::||
Zfish     5 SITSILVVLTL---VAQDRLAGGLEHKSYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYE 66

  Fly   154 GRTIRGIKISHKAGNP--GIFIESNIHAREWITSASATWFINQLLTS--EDADVRSLADNYDWHI 214
            .|.|..:||...:..|  .|:::..|||||||..|....|:.::|.|  .|:.|..|..|.|::|
Zfish    67 KRNITLLKIGFSSTTPKKAIWMDCGIHAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYI 131

  Fly   215 IPVFNVDGFEYS--HKKDRMWRKTRQP-HATNACIGADANRNFDSYWLQNNGASDNPCSETFAGD 276
            .||.|:||:.||  :...|:|||:|.| |..:.|.|.|.||||.:.| ...|.|.|.|||.:.|.
Zfish   132 TPVLNMDGYIYSWLNNSTRLWRKSRSPCHENSTCSGTDLNRNFYANW-GMVGISRNCCSEVYNGA 195

  Fly   277 NPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIE 341
            ...|||||:|:.::|...|:.:..|::.|||||.:|.||||.|...| ||::::.:|.|.|.||:
Zfish   196 TALSEPEAEAVTDFLGAHQNHLLCYLTIHSYGQLILVPYGHPNISAP-NYDELMEVGLAAAKAIK 259

  Fly   342 ALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQIIPNCEELM 406
            |: :|..|:.||:.||||..:|:|.|:. ..:|....:|.|.||:|::|||||..||.|.|:|..
Zfish   260 AV-HGKSYKVGSSPDVLYPNSGSSRDFA-RLIGIPYSFTFELRDEGQHGFILPEDQIQPTCQEAY 322

  Fly   407 VGMLALI 413
            .|.:::|
Zfish   323 EGAMSII 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	3/15 (20%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	120/299 (40%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	120/299 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593506
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.780