DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18585 and cpb2

DIOPT Version :9

Sequence 1:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001018539.2	Gene:	cpb2 / 100000935	ZFINID:	ZDB-GENE-050522-259	Length:	424	Species:	Danio rerio

Alignment Length:	412	Identity:	132/412 - (32%)
Similarity:	226/412 - (54%)	Gaps:	28/412 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYN---IWK----EYDERSRQIDIMVSPGELNHF 81
            |.::|  :|..:|:.::   ..:||:..|| .:|   :|:    .|...:.::.:.:....:...
Zfish    23 KVKHD--QVLAITVSSQ---EHVEKVQNLT-SHNETALWQPASPNYITTNSEVHLYIQSTSVQFV 81

  Fly    82 QELLKFNNISSELMIENVQERIDEEQVTPTADSATFG--WTKYYELEEIEAWLDEILNAYPSVTE 144
            :|.|:.:.|:..:::||....:..:....|:|..:.|  :.:|:.||:|..|:::....:..:.:
Zfish    82 KEHLREHAITFRVLVENTAALVAMQIRNDTSDPRSGGVFYERYHSLEDIYYWINKTSREHSDMVK 146

  Fly   145 EFIVGKSYEGRTIRGIKISHKAG---NPGIFIESNIHAREWITSASATWFINQLLT--SEDADVR 204
            ..::|.|.|.|.:..:|:|.|..   |..::::..|||||||..|...||:|..|.  :::.::.
Zfish   147 VILIGSSSEKRPLYVLKLSGKREEEVNRAMWMDCGIHAREWIAPAFCMWFVNYALAFYNQNTEIT 211

  Fly   205 SLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPC 269
            .:.:..|.:|:.|.|.||::|:...||||||.|..:..:.|.|.|.|||||:.|. ..||||:||
Zfish   212 EMLNKMDIYILTVMNPDGYKYTWTTDRMWRKNRSENKDSYCAGVDLNRNFDANWC-TKGASDDPC 275

  Fly   270 SETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGK 334
            ..|:.|..||||||.:|:.::|...:|.:.:|:|.|||.|.||.||..:..|.| |:|::..:.|
Zfish   276 DPTYCGQFPESEPETQAVAKFLRSHKDTVKLYLSIHSYSQMLLFPYSCSYNEIP-NHNELFELVK 339

  Fly   335 AFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQII 399
            ..:..|... |...|:|||.|..:|:|.|.|.||.: :||.|..:|.|.:|:|:|||:|||..|.
Zfish   340 EASTKIRRY-YRNNYKYGSGAKTIYLAPGGSDDWAY-DLGIKYSFTFELQDRGQYGFLLPPSFIP 402

  Fly   400 PNCEELMVG----MLALIEKTK 417
            ..|.|.::.    .|.:|.||:
Zfish   403 QACNEALLAAKVIALHVINKTQ 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	13/77 (17%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	111/301 (37%)
cpb2	NP_001018539.2	Propep_M14	32..98	CDD:280416	11/69 (16%)
cpb2	NP_001018539.2	M14_CPB2	120..420	CDD:199868	110/303 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.680