DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6739 and CD320

DIOPT Version :9

Sequence 1:	NP_609130.1	Gene:	CG6739 / 34037	FlyBaseID:	FBgn0031926	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_057663.1	Gene:	CD320 / 51293	HGNCID:	16692	Length:	282	Species:	Homo sapiens

Alignment Length:	196	Identity:	50/196 - (25%)
Similarity:	74/196 - (37%)	Gaps:	60/196 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   432 CYGNEFQCH-DGSCIPQNWQCDKIKDCQGGEDEDE----------QC------------------ 467
            |...:|||. .|.|:|..|:||:..||..|.||:|          ||
Human    54 CPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPCTQKGQCPPPPGLPCPCTGVSDCSG 118

  Fly   468 -----------LVCEPDEFRCRSNEKCLVEKYRCDQNIDCMDGSDEQDCDEYGSGDLAPFDESEL 521
                       |.|...|.||..::.|:...:|||.:.||.|.|||..|   |:.::.|..:
Human   119 GTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSSDELGC---GTNEILPEGD--- 177

  Fly   522 NAFPRVFTYASFLSPNETNDKVYTYITATTDEDAGTETKFQIHQVAAPAPPVNSSAEEGAGGPKG 586
                     |:.:.|..|.:.|.:...|||.....|     :..|.:.....:|||.:.:|.|..
Human   178 ---------ATTMGPPVTLESVTSLRNATTMGPPVT-----LESVPSVGNATSSSAGDQSGSPTA 228

  Fly   587 F 587
            :
Human   229 Y 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6739	NP_609130.1	CRD_FZ	314..427	CDD:143549
		LDLa	432..464	CDD:238060	14/32 (44%)
		LDLa	470..505	CDD:238060	14/34 (41%)
		LDLa	697..731	CDD:238060
CD320	NP_057663.1	LDLa	54..89	CDD:238060	15/34 (44%)
CD320	NP_057663.1	LDLa	132..167	CDD:238060	14/34 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900