DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6739 and F14B4.1

DIOPT Version :9

Sequence 1:	NP_609130.1	Gene:	CG6739 / 34037	FlyBaseID:	FBgn0031926	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_492474.2	Gene:	F14B4.1 / 172750	WormBaseID:	WBGene00008779	Length:	722	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	47/201 - (23%)
Similarity:	68/201 - (33%)	Gaps:	71/201 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 QSTMLPMCQGVLDYDLTFNREGAAPRDAVSMAAYDSLIRANCSVRAAEFIC-----GALEPECRP 374
            |:.:||       |.|....:...|.:.           :.|..|..:.:|     ||....|
Worm   561 QTALLP-------YSLKVFHKSLQPEET-----------STCETRGCDQLCLLGENGAATCAC-- 605

  Fly   375 LHIGQLPPCRRICKAILEACSIPIYNSDVLGELFDCNLYPDAHESHKCEDPTRRRDYCYGNEFQC 439
                                          ||.||.     .::..||.      ..|..::.:|
Worm   606 ------------------------------GEGFDL-----LNDGKKCS------SNCSESQIEC 629

  Fly   440 --HDGSCIPQNWQCDKIKDCQGGEDEDEQC--LVCEPDEFRCRSNEKCLVEKYRCDQNIDCMDGS 500
              .|..||.:.:.||.:..|....|| |:|  .:|.|.:|:|..|.|||.....||:..||.|.|
Worm   630 GGADPKCISKIYLCDGLAQCSNQADE-EKCPPRICLPGQFQCHDNHKCLPPGGLCDKVTDCSDSS 693

  Fly   501 DEQDCD 506
            ||..|:
Worm   694 DEIYCE 699

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6739	NP_609130.1	CRD_FZ	314..427	CDD:143549	18/116 (16%)
		LDLa	432..464	CDD:238060	9/33 (27%)
		LDLa	470..505	CDD:238060	16/34 (47%)
		LDLa	697..731	CDD:238060
F14B4.1	NP_492474.2	vWFA	<272..313	CDD:294047
		LY	343..383	CDD:214531
		LY	391..425	CDD:214531
		Ldl_recept_b	448..486	CDD:278487
		LY	470..512	CDD:214531
		LY	513..549	CDD:214531
		FXa_inhibition	588..618	CDD:291342	8/66 (12%)
		LDLa	622..658	CDD:238060	11/36 (31%)
		LDLa	663..698	CDD:238060	16/34 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900