Protein Alignment CG6739 and LRP1

DIOPT Version :10

• Sequence 1: NP_609130.1
• Gene: CG6739 / 34037
• FlyBaseID: FBgn0031926
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_320185.5
• Gene: LRP1 / 1280340
• VectorBaseID: AGAMI1_005394
• Length: 4869
• Species: Anopheles gambiae
• Alignment Length: 876
• Identity: 190/876 - (21%)
• Similarity: 279/876 - (31%)
• Gaps: 319/876 - (36%)

  Fly    29 HGLNITVQTIDDDNEGSPKDHSDYTRA---------SGDSCWSKTQKYHIGMLGSPETLAELQVR 84
            |.|...: |:|.|.:......||.||.         ||:.. ...:..|...|.:||.||...|.
Mosquito  3229 HNLTNAI-TLDFDWKDECYYWSDVTRTVTTVKRMCESGEEN-RPVEVIHRTNLKNPEGLAVDWVG 3291

  Fly    85 RYKY------------PLTANY---YLNSKLERPE----KP-------TPW---------MLLGY 114
            |..|            .|...|   .:|.:|::|.    .|       |.|         .:.|.
Mosquito  3292 RNLYWCDKGLDTIEVSKLDGRYRRVLINKELQKPRAIALDPYRRYMYWTDWGDQPHIGRAGMDGS 3356

  Fly   115 ARSVCRWKYLRWP----IIFVASVLLFFGLITYCLWLHDVSVARAK-FLQRRYEATLTSTSSSSN 174
            .:::...:.|.||    |.|..:.|.:.......:.:.|:.....: .|.|..:.||......:.
Mosquito  3357 NQTILIKEQLGWPNALTISFETNQLFWGDAREDYIAVSDLDGQNVRILLSRARQPTLNLHHVFAI 3421

  Fly   175 EVWDEETTSSTERSPQETTRLEDMDDSDESTELPEIAFGDDGDPEAGGEDGDGDYDDTLLPADSI 239
            .||::....|            |:|  .:|.|......|          ||.|    ||:
Mosquito  3422 AVWEDRIYWS------------DLD--SKSIEYCHKFRG----------DGCG----TLI----- 3453

  Fly   240 RFTSGHQNSFGVPIEQDKRMLQLLKELLHKPQATP---AGNEPTLTRVSPTLPPP---------- 291
                   |:...|:  |.|:....::|  :|:..|   ||.: ||..:||  .||
Mosquito  3454 -------NTIHRPM--DIRVFHYYRQL--QPEVNPCDTAGCQ-TLCVLSP--DPPGYRCLCPDNF 3504

  Fly   292 -LSASGRPTEAMALTTPSTTNSGCQSTM--LP--------------------------------- 320
             |:|.|:...|..    |..:..|::|.  :|
Mosquito  3505 ILTADGKSCAANC----SAAHFQCRTTFKCIPFYWRCDKQDDCGDGSDEPPNCPTFTCEAGQFQC 3565

  Fly   321 ----------MCQGVLDY--DLTFNREGAAPRDAVSMAAYDSLIRANCSVRAA------------ 361
                      :|.|| |.  ||      :..||......:.|..:  |...||
Mosquito  3566 LNKRCINPSQICDGV-DQCGDL------SDERDCDRFECFSSHFK--CGPSAAKNTSGFCIEGAR 3621

  Fly   362 ----EFIC--GALEPECRPLHIGQLPPCRRICKAILEACSIPIYNSDVLGELFD----CNLYPDA 416
                |..|  |..|..|.|          :.|.|....|:    |.   |...|    |:..||.
Mosquito  3622 RCDEEVNCPNGEDEQNCEP----------KNCTATQFRCA----NG---GRCIDRTWVCDNVPDC 3669

  Fly   417 H---ESHKCEDPTRRRDYCYGNEFQCHDGSCIPQNWQCDKIKDCQGGEDEDEQC-----LVCEPD 473
            |   :...|...|.    |..:||:|.:|.||||:|.||..|||..||||.|.|     :.|||.
Mosquito  3670 HDGSDEQVCGPATT----CPEHEFRCSEGRCIPQSWLCDDEKDCANGEDETENCQKPEAITCEPT 3730

  Fly   474 EFRCRSNEKCLVEKYRCDQNIDCMDGSDEQDCDEYGSGDLAPFDESELNAFPRVFTYASFLSPNE 538
            .||| :|.||:..::|||...||.|.|||.:|      :|....|||................||
Mosquito  3731 SFRC-NNSKCIPGRWRCDFENDCGDNSDELNC------ELRNCSESEFRCRDGHCIRGIRRCDNE 3788

  Fly   539 TN-----DKVYTYITATTDE------DAGTETKFQIHQVAAPAPPVNSSAEEGAGGPKGFVNFRD 592
            .|     |:....:|.:.::      .|....||:..   .....::.|.||.....:|.....:
Mosquito  3789 FNCADHSDEENCNVTCSAEQFKCKSHPACISNKFKCD---GDNDCIDESDEEDCECQEGEYRCNN 3850

  Fly   593 SKEIMMT----------SDSETKFKYSQR----------ANRTSVKFSVSAPTTPAARTSSAIPS 637
            .|.|:.:          .:|:...:|.:.          |||..::.|:..........:|. ..
Mosquito  3851 GKCILSSWVCDGIDDCLDNSDEMGEYCKEHGCNKRAFRCANRNCIRKSLMCDNKDDCGDNSD-EK 3914

  Fly   638 SALVQQRERTTSTTTTSTTTSTTTSSITSTPSITSTTLIPINAATSEPNPYEVVTSLGGCPPQEL 702
            |||..:                                                     |||...
Mosquito  3915 SALCHK-----------------------------------------------------CPPNSF 3926

  Fly   703 RCVS-GKCITVSQLCDKQIDCPDAADELMCV 732
            ||.| .|||.::..||:...|.|.:||:.|:
Mosquito  3927 RCNSDSKCIDIALRCDQTPHCLDESDEIGCI 3957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6739	NP_609130.1	CRD_FZ	314..427	CDD:143549	32/184 (17%)
		LDLa	432..464	CDD:238060	18/31 (58%)
		LDLa	470..505	CDD:238060	18/34 (53%)
		LDLa	697..731	CDD:238060	15/34 (44%)
LRP1	XP_320185.5	None