Protein Alignment Cyp4d21 and ERG5

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 529
• Identity: 121/529 - (22%)
• Similarity: 209/529 - (39%)
• Gaps: 111/529 - (20%)

  Fly     9 VLIMTLVWDNSRKQWRVNTFEKSRILGP-FTI-PIVGNGLQALTLRPENFIQRFGDYFNKYG--- 68
            ::.:.||||....|     .:|..|.|| |.. ||:|..|::|.       .:|.:|..|:.
Yeast    52 LICILLVWDQVAYQ-----IKKGSIAGPKFKFWPIIGPFLESLD-------PKFEEYKAKWASGP 104

  Fly    69 ----KTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHL---YRFLRD----FLGDGLLLSTGN 122
                ..|..:::   :..|:||.  ..||.||..:|...:   .:.||.    ||       .|.
Yeast   105 LSCVSIFHKFVV---IASTRDLA--RKILQSSKFVKPCVVDVAVKILRPCNWVFL-------DGK 157

  Fly   123 KWTSRRKVLAPAFHFKCLENFV----EIMDR--NSGIMVEKLKNYADGKTCVDLFKFVSLEALD- 180
            ..|..||.|...|..:.|..::    :|||:  :..:.:.|..||.......::.:.:...:|:
Yeast   158 AHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSLNS 222

  Fly   181 -----VTTETAMGVQ-----VNAQNE-PNF----PYTKALKSVVYIESKRLASVSMRYNWLFPLA 230
                 :|.:....:.     |.|..| .||    ||||..      ..|:.|.::|:   :|...
Yeast   223 FCGNYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTW------YGKKTADMAMK---IFENC 278

  Fly   231 APLVYRRLQ---KDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILL 292
            |.:....:.   |.:.:| |...|::.:.:.               ..|||
Yeast   279 AQMAKDHIAAGGKPVCVM-DAWCKLMHDAKN---------------SNDDD-------------- 313

  Fly   293 QATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDAS 357
             :.|.::..::.:|.|.|..|:||..|.::|........::..|.|...|.||.::|...|....
Yeast   314 -SRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTE 377

  Fly   358 VTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIG-EITIPGNTSILLMPYYVYRDPEYF 421
            :....:.::||.:.|||||:|..|||.::...:.::..:. ..|.|....::...|....|||.:
Yeast   378 LNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVY 442

  Fly   422 PDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIR----HYELLPL 482
            .:|..|.||||::....|.... .::.|..||..|:||.:..:...||:.|...    |:.:.||
Yeast   443 ENPDEFIPERWVEGSKASEAKK-NWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPL 506

  Fly   483 GADLKATYT 491
            ...:|...|
Yeast   507 SEKIKVFAT 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	110/492 (22%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	103/466 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I1557
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I1313
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
TreeFam	0	0.000	Not matched by this tool.
	4	3.960