DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d21 and CYP86A7

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_176558.1	Gene:	CYP86A7 / 842675	AraportID:	AT1G63710	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	118/521 - (22%)
Similarity:	206/521 - (39%)	Gaps:	99/521 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IAVLIMT-LVWDNS-RKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNKYGK 69
            |..||:| ::|..| |:.::          ||...|:||: |.||............|.....|.
plant     9 ILTLIVTYIIWFVSLRRSYK----------GPRVWPLVGS-LPALITNAHRMHDFIADNLRMCGG 62

  Fly    70 TFRLWIL---------GECLIYTKDLKYFESILSS--STLLKKAHLYRFLRDFLGDGLLLSTGNK 123
            |::..|.         |...: |.|.|..|.||.:  ....|.........|.||||:..|.|:.
plant    63 TYQTCIFPIPFLAKKQGHVTV-TCDPKNLEHILKTRFDNYPKGPSWQSVFHDLLGDGIFNSDGDT 126

  Fly   124 WTSRRKVLAPAFHFKCLE----NFVEIMDRNSGI-MVEKLKNYADGKTCVDLFKFVSLEALDVTT 183
            |..:||..|..|..:.|.    .:|:...:|..: ::|..::.|:.....|:.       |.:|.
plant   127 WRFQRKTAALEFTTRTLRQAMARWVDRAIKNRLVPILESARSRAEPIDLQDVL-------LRLTF 184

  Fly   184 ETAMGVQVNAQN---EPNFP---YTKALKSVVYIESKRLASVSMRY---NWLFPLAAPLVYRRL- 238
            :...|:......   .|.||   :..|.........:|.......:   .||          ||
plant   185 DNICGLTFGKDPRTLSPEFPENGFAVAFDGATEATLQRFIMPEFIWKIRKWL----------RLG 239

  Fly   239 -----QKDIAIMQDFTDKVIRERRAIL-----ERARADGTYKPLIMGDDDIGGKAKMTLLDILLQ 293
                 .:.|:.:.::..::|..|:..|     :.:|.|                      |:|.:
plant   240 LEDDMSRSISHVDNYLSEIINTRKLELLGQQQDESRHD----------------------DLLSR 282

  Fly   294 ATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASV 358
            .....:..||..::.....||.||.||::..:|.....:|.:|:|:|.|..|:.::|....|.:|
plant   283 FMKKKESYSDKYLKYVALNFILAGRDTSSVAMSWFFWLVSLNPRVEEKIINEICTILIKTRDTNV 347

  Fly   359 --------TQTKLLELKYLDCVIKETMRLHPPVPILGRY-IPEDLKIGEITIPGNTSILLMPYYV 414
                    |..::.:|.||...:.||:||:|.||...:: :..|:......:|..:::....|.|
plant   348 SKWTDEPLTFDEIDQLVYLKAALSETLRLYPSVPEDSKFVVANDVLPDGTFVPSGSNVTYSIYSV 412

  Fly   415 YRDPEYF-PDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYE 478
            .|....: .|.|.||||||::...........::.|::||:.|:|:..|.||||::.:.::..:.
plant   413 GRMKFIWGEDCLEFKPERWLEESRDEKCNQYKFVAFNAGPRICLGKDLAYLQMKSITASILLRHR 477

  Fly   479 L 479
            |
plant   478 L 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	111/491 (23%)
CYP86A7	NP_176558.1	PLN03195	4..507	CDD:215627	118/521 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910