DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d21 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	112/483 - (23%)
Similarity:	215/483 - (44%)	Gaps:	36/483 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IPIVGNGLQALTLRPENFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAH 103
            :|.....:||  :|.|.|.....:.|..||..|||....:..:...|....:.||..:.......
plant   113 VPEAKGSIQA--VRNEAFFIPLYELFLTYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKG 175

  Fly   104 LYRFLRDF-LGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTC 167
            :...:.|| :|.||:.:.|..|..||:.:.||.|.|.:...:.:....|..:.:||...|.....
plant   176 ILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEE 240

  Fly   168 VDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYI----ESKRLASVSMRYNWLFP 228
            |::....|...||:..:.......::....    |..:::|..:    |.:.::.:.:   |..|
plant   241 VEMESLFSRLTLDIIGKAVFNYDFDSLTND----TGVIEAVYTVLREAEDRSVSPIPV---WDIP 298

  Fly   229 LAAPLV--YRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDIL 291
            :...:.  .|::...:.::.|..|.:|...:.::|.....  :....|.:.|      .::|..|
plant   299 IWKDISPRQRKVATSLKLINDTLDDLIATCKRMVEEEELQ--FHEEYMNERD------PSILHFL 355

  Fly   292 LQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDA 356
            |.:..|   :|...:|:::...:.||.:|:.:.::...:.::..|.|...:.||:.||:|   |.
plant   356 LASGDD---VSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIG---DR 414

  Fly   357 SVTQTKLLELKYLDCVIKETMRLHPPVPIL-GRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEY 420
            ..|...:.:|||...|:.|::||:|..|:| .|.|..|: :||..|.....|.:..:.::|.|.:
plant   415 FPTIQDMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDI-LGEYPIKRGEDIFISVWNLHRSPLH 478

  Fly   421 FPDPLVFKPERW-MDMKTTSNT-PPLAYIPFSSGPKNCIGQKFANLQMKALISKVIR--HYELLP 481
            :.|...|.|||| :|....:.| ...:|:||..||:.|||..||:.:....|:.:||  ::::.|
plant   479 WDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQIAP 543

  Fly   482 LGADLKATYTFILSSSTGNNVGLKPRTR 509
            ....:|.|....:.::.|..:.:..||:
plant   544 GAPPVKMTTGATIHTTEGLKLTVTKRTK 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	106/454 (23%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	112/483 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010