DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d21 and CYP735A1

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_198661.1	Gene:	CYP735A1 / 833833	AraportID:	AT5G38450	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	148/569 - (26%)
Similarity:	250/569 - (43%)	Gaps:	123/569 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ILLGIAVLIMTLV-----------WDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPEN- 55
            ||..:.|:.:|.:           |...|:..::  .|:..:.||...|:.||.|:...:..::
plant     5 ILKSLLVIFVTTILRVLYDTISCYWLTPRRIKKI--MEQQGVTGPKPRPLTGNILEISAMVSQSA 67

  Fly    56 --------------FIQRFGDYFNKYGKTFRLWILGE---CLIYTKDLKYFESILSSSTLLKKAH 103
                          .:..:..:..:|||.|.:|...:   ||..|:.:|  |.::..:.:..::.
plant    68 SKDCDSIHHDIVGRLLPHYVAWSKQYGKRFIVWNGTDPRLCLTETELIK--ELLMKHNGVSGRSW 130

  Fly   104 L-YRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKL-KNYADGKT 166
            | .:..::|:|.|||::.|..|..:|.:.||||..:.|:.:...|...:..:||:| |...:|..
plant   131 LQQQGTKNFIGRGLLMANGQDWHHQRHLAAPAFTGERLKGYARHMVECTSKLVERLRKEVGEGAN 195

  Fly   167 CVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLA- 230
            .|::.:.:.....|:.:.|..|        .:|...|.|.:.:.:..:|.|..:.  :..||.:
plant   196 EVEIGEEMHKLTADIISRTKFG--------SSFEKGKELFNHLTVLQRRCAQATR--HLCFPGSR 250

  Fly   231 -APLVYRR----LQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDI 290
             .|..|.|    |:|::   :....::|:.||...|..|: .|:     |||         ||.:
plant   251 FLPSKYNREIKSLKKEV---ERLLIEIIQSRRDCAEMGRS-STH-----GDD---------LLGL 297

  Fly   291 LLQATIDNKPLSDVD------------IREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIY 343
            ||..       .|:|            |.:|...|.|||.:||...::.....::.:|..||.:.
plant   298 LLNE-------MDIDKNNNNNNNNLQLIMDECKTFFFAGHETTALLLTWTTMLLADNPTWQEKVR 355

  Fly   344 EELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSIL 408
            ||:..|.|.:...||.|  |.:|..|..||.|::||:||..:|.|...||||:|::|||...||.
plant   356 EEVREVFGRNGLPSVDQ--LSKLTSLSKVINESLRLYPPATLLPRMAFEDLKLGDLTIPKGLSIW 418

  Fly   409 LMPYYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPLA----YIPFSSGPKNCIGQKFANLQMKA 468
            :....::...|.: .|...|.|||:       ...|.|    :|||::||:|||||:||.::.|.
plant   419 IPVLAIHHSEELWGKDANQFNPERF-------GGRPFASGRHFIPFAAGPRNCIGQQFALMEAKI 476

  Fly   469 L-----------ISKVIRHYELLPLGADLKATYTFILSSSTGNNVGLKP 506
            :           |||..||..::.|  .:|..|        |..|.|||
plant   477 ILATLISKFNFTISKNYRHAPIVVL--TIKPKY--------GVQVILKP 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	133/500 (27%)
CYP735A1	NP_198661.1	PLN02290	1..518	CDD:215164	148/569 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.060