DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d21 and CYP97B3

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_193247.2	Gene:	CYP97B3 / 827177	AraportID:	AT4G15110	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	120/514 - (23%)
Similarity:	227/514 - (44%)	Gaps:	84/514 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SRILGPFTIPIVGNGLQALTLRPENFIQRFG--------DYFNKYGKTFRLWILGECLIYTKDLK 87
            |.:|..|   :.|..|.::.....:....||        |:|.::|..::|....:..:...|
plant    69 SNLLTNF---LSGGSLGSMPTAEGSVSDLFGKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISD-- 128

  Fly    88 YFESILSSSTLLKKAHLY------RFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEI 146
               .|::...|.:.|..|      ..|...:|.||:.:..:.|..||:.:.||||...||..|::
plant   129 ---PIIARHVLRENAFSYDKGVLAEILEPIMGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKV 190

  Fly   147 MDRNSGIMV---EKL---KNYADGKTCVDL---FKFVSLEALDVTTETAMGVQVNAQNEPNFPYT 202
            ....|..|:   |||   |..:.|:..::|   .:|.|| |||:...:.......:..:.: |..
plant   191 FSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSL-ALDIIGLSVFNYDFGSVTKES-PVI 253

  Fly   203 KALKSVVYIESKRLASVSMRYNWLFPLAAPLV--YRRLQKDIAIMQDFTDKVIRERRAILERARA 265
            ||:...:: |::..::....| |.||.|..:|  .|:.|.|:.|:.|..|.:|:..:...:....
plant   254 KAVYGTLF-EAEHRSTFYFPY-WNFPPARWIVPRQRKFQSDLKIINDCLDGLIQNAKETRQETDV 316

  Fly   266 DGTYKPLIMGDDDIGGKAKMTLLDILLQAT-IDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHAL 329
            :.      :.:.|.......:||..|:... :|   :.|..:|:::...:.||.:||.:.::.|:
plant   317 EK------LQERDYTNLKDASLLRFLVDMRGVD---IDDRQLRDDLMTMLIAGHETTAAVLTWAV 372

  Fly   330 HAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYI--PE 392
            ..:|::|:.......|:.:|||..|.   |...:.:|:|:..::.|.:||.|..|:|.|..  ||
plant   373 FLLSQNPEKIRKAQAEIDAVLGQGPP---TYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPE 434

  Fly   393 DLKIGE------ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTT-----------SN 440
            .|..|.      ..:|..|.|.:..|.::|.|.::.:|..|:|||::..|.:           |.
plant   435 TLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFWDNPHDFEPERFLRTKESNGIEGWAGFDPSR 499

  Fly   441 TP----------PLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKAT 489
            :|          ..|::||..||:.|||.:||.::....::.:.:.:::     :|:.|
plant   500 SPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDV-----ELRGT 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	116/501 (23%)
CYP97B3	NP_193247.2	PLN02738	45..580	CDD:215393	120/514 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010