DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d21 and CYP94D2

DIOPT Version :9

Sequence 1:	NP_609129.2	Gene:	Cyp4d21 / 34036	FlyBaseID:	FBgn0031925	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_191222.1	Gene:	CYP94D2 / 824830	AraportID:	AT3G56630	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	137/517 - (26%)
Similarity:	218/517 - (42%)	Gaps:	100/517 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PIVGNGLQALTLRPENFIQRFGDY--------------FNKYGKTFRLWILG----ECLIYTKDL 86
            ||||: |..|.    |...||.|:              |.:.||...:....    |.::.||
plant    35 PIVGS-LPGLV----NNRHRFLDWTVETLSRCPTQTAIFRRPGKLQFVMTANPANVEYMLKTK-- 92

  Fly    87 KYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENF------VE 145
              |||.......:.      .|.||||.|:..|.|..|..:||..:..|..|.|.:|      ||
plant    93 --FESFPKGERFIS------ILEDFLGRGIFNSDGEMWWKQRKTASYEFSTKSLRDFVMSNVTVE 149

  Fly   146 IMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQ---VNAQNEPNFPYTKALKS 207
            |..|...::.|...|   || .:||...:...|.|...:.|..|.   :.........:.:|.::
plant   150 INTRLVPVLAEAATN---GK-LIDLQDILERFAFDNICKLAFNVDSACLGDDGAAGVNFMQAFET 210

  Fly   208 VVYIESKRLASVSMRYNWLFPLAAPLVYRR-LQKDIAIMQDFTDKVIRERRAILERARADGTYKP 271
            ...|.|:|..|| :.|:|.......:...| |::.|.|:..|.|:::|.|   :|:.:. ..:|
plant   211 AATIISQRFQSV-ISYSWKIKKKLNIGSERVLRESIMIVHKFADEIVRNR---IEQGKV-SDHK- 269

  Fly   272 LIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDI-REEVDVFIFAGDDTTTSGVSHALHAISRH 335
                             :.||...|..:.::..:| |:.|..||.||.|||:|.:|.....:|.|
plant   270 -----------------EDLLSRFISKEEMNSPEILRDIVISFILAGRDTTSSALSWFFWLLSMH 317

  Fly   336 PKVQECIYEELVSVLGPDPDASVTQTKLLE---------LKYLDCVIKETMRLHPPVPILGRYIP 391
            |:|::.|.:||.|:      ...|..::.|         :.||...|.|::||:||||:......
plant   318 PEVKDKILQELNSI------RERTGKRIGEVYGFEDLKLMNYLHAAITESLRLYPPVPVDTMSCA 376

  Fly   392 EDLKIGEITIPG-NTSILLMPYYVYR-DPEYFPDPLVFKPERWMDMKTTS---NTPPLAYIPFSS 451
            ||..:.:.|..| :..|....|.:.| :..:..|...|.||||:| :|..   ...|..:..|.:
plant   377 EDNVLPDGTFIGKDWGISYNAYAMGRMESIWGKDCDRFDPERWID-ETNGGFRGENPYKFPAFHA 440

  Fly   452 GPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSST-----GNNVGLKPRT 508
            ||:.|:|::.|.:|||::::.|:..:.:...|   |.....||.|.|     |.||.::.|:
plant   441 GPRMCLGKEMAYIQMKSIVAAVLERFVVEVPG---KKERPEILMSVTLRIRGGLNVRVQERS 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	127/484 (26%)
CYP94D2	NP_191222.1	p450	52..499	CDD:299894	127/493 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910