DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp4d21 and Cyp4f14

DIOPT Version :9

Sequence 1:NP_609129.2 Gene:Cyp4d21 / 34036 FlyBaseID:FBgn0031925 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001191262.1 Gene:Cyp4f14 / 64385 MGIID:1927669 Length:524 Species:Mus musculus


Alignment Length:524 Identity:171/524 - (32%)
Similarity:261/524 - (49%) Gaps:53/524 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 WILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQ---ALTLRPENFIQRFGDY 63
            |||..|.:.|..             .:...|.|..|..|...|.|.   .:....|..::.....
Mouse    29 WILARILIQIYA-------------AYRNYRHLHGFPQPPKRNWLMGHVGMVTPTEQGLKELTRL 80

  Fly    64 FNKYGKTFRLWILGECLIYT---KDLKYFESIL--SSSTLLKKAHLYRFLRDFLGDGLLLSTGNK 123
            ...|.:.|.:||.....:.|   .|:  ..|||  |::..||....|..|:.:||||||:|.|:|
Mouse    81 VGTYPQGFLMWIGPMVPVITLCHSDI--VRSILNASAAVALKDVIFYSILKPWLGDGLLVSAGDK 143

  Fly   124 WTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKN-YADGKTCVDLFKFVSLEALDVTTETAM 187
            |:..|::|.|||||..|:.:|:|.:.::.||..|.:. .:||...:|:|:.|||..||...:...
Mouse   144 WSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHVSLMTLDSLQKCVF 208

  Fly   188 GVQVNAQNEPNFPYTKALKSVVYIESKR----LASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDF 248
            ....|.| |.:..|..|:..:..:.:||    |..:.:.|| |.|..     .|.:|...::.:|
Mouse   209 SFDSNCQ-EKSSEYIAAILELSALVAKRHQQPLMFMDLLYN-LTPDG-----MRFRKACNVVHEF 266

  Fly   249 TDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLD----ILLQATIDNKPLSDVDIREE 309
            ||.|||||...|          |....||.:..|||...||    :||....|.|.|||.|||.|
Mouse   267 TDAVIRERHRTL----------PDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAE 321

  Fly   310 VDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVL-GPDPDASVTQTKLLELKYLDCVI 373
            .|.|:|.|.|||.||:|..|:.::|||:.||...:|:..:| |.:|: .:....|.:|.:|...|
Mouse   322 ADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPE-EIEWDDLAQLPFLTMCI 385

  Fly   374 KETMRLHPPVPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKT 437
            ||::||||||.::.|...:|:.:.: .|||.....|:..:.::.:|..:|||.|:.|.|: |.:.
Mouse   386 KESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYDPFRF-DPEN 449

  Fly   438 TSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSSTGNNV 502
            ..::.|||:||||:||:|||||.||..:||..::..:..:.|||...:.:.....||.:..|..:
Mouse   450 IKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPRRQPELILRAEGGLWL 514

  Fly   503 GLKP 506
            .::|
Mouse   515 RVEP 518

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp4d21NP_609129.2 p450 35..482 CDD:278495 159/465 (34%)
Cyp4f14NP_001191262.1 p450 52..511 CDD:365848 161/479 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167845215
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3B9GY
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D214327at33208
OrthoFinder 1 1.000 - - FOG0000016
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X23
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.750

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