Protein Alignment Cyp4d21 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 496
• Identity: 129/496 - (26%)
• Similarity: 249/496 - (50%)
• Gaps: 56/496 - (11%)

  Fly     2 WILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRF-GDYFN 65
            |:|     |:.:||:......:....|:|..|.||..:|:.||.:..|     :.:.:| .|.:.
Mouse    12 WVL-----LVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYL-----DGMWKFDDDCYK 66

  Fly    66 KYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLR------DFLGDGLLLSTGNKW 124
            ||||.:..:...:.::...|.:..:.:     |:|:.:.....|      .||...:.:|...:|
Mouse    67 KYGKIWGFYEGPQPILAIMDPEIIKIV-----LVKECYSVFTNRRPFGPVGFLKKSITISEDEEW 126

  Fly   125 TSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGV 189
            ...|.:|:|.|....|:....||.:...|:|..|:...:.:..:::.......::||.|.|:.||
Mouse   127 KRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGV 191

  Fly   190 QVNAQNEPNFPYTKALKSVV---YIESKRLASVSMRYNWLFPLAAPLVYRRL------QKDIAIM 245
            .:::.|.|..|:.:.:|.::   :.:...|:.|      |||...| :|..|      ::.:...
Mouse   192 NIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVV------LFPFLTP-IYEMLNLSIFPRQSMNFF 249

  Fly   246 QDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEV 310
            :.|..|:.::|....::.|.|  :..|:|...:..|:..:             |.|||:::..:.
Mouse   250 KKFVKKMKKDRLDYNQKNRVD--FLQLMMNTQNSKGQESL-------------KALSDLEMAAQT 299

  Fly   311 DVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKE 375
            .:|||.|.|.|::.:|..::.::.||.||:.:.:|:...| |: .|.||...|::::|||.|:.|
Mouse   300 LIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRAL-PN-KAPVTYDALMDMEYLDMVVNE 362

  Fly   376 TMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSN 440
            ::||:|.|..:.|:..:|::|..:.||..|.:::..|.::|||||:|:|..|.|||: ..:...|
Mouse   363 SLRLYPVVSRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERF-SKENKGN 426

  Fly   441 TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481
            ..|..|:||.:||:||||.:||.:.:|..::.|::::.:.|
Mouse   427 IDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	121/463 (26%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	121/464 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910