Protein Alignment Cyp4d21 and cyp46a1.1

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001027519.1
• Gene: cyp46a1.1 / 613111
• XenbaseID: XB-GENE-22069537
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 140/545 - (25%)
• Similarity: 245/545 - (44%)
• Gaps: 88/545 - (16%)

  Fly     1 MWILLG---IAVLIMTLV---------------WDNSRKQWRVNTFEKSRILGPFTIP----IVG 43
            :|.|.|   :.:|.:||:               :|:              |.||   |    |.|
 Frog     3 LWALFGWASLLLLALTLICFLLFCGYIQYIHMKYDH--------------IPGP---PRDGFIFG 50

  Fly    44 NGLQALTLRPENFI--QRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKK----- 101
            :....|.|...|.:  .::.|:..|||...|:..|...::.....:..:..|.|....|.
 Frog    51 HSPTILRLMKNNKVVYDQYLDWVQKYGPVVRINALHRVIVLITSPEGVKEFLMSPKYSKNDIYDR 115

  Fly   102 -AHLYRFLRDFLGDGLLLSTG-NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADG 164
             |.||..  .|:|.||:.... :.|..:|:::.|||....|.:.:...:..:..::|:|...|||
 Frog   116 VATLYGM--RFMGKGLVTDKDHDHWYKQRRIMDPAFSRTYLMDLMGPFNEKAEELMERLSEQADG 178

  Fly   165 KTCVDLFKFVSLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVV--YIESKRLASVSMRYNWLF 227
            |:..::....|...|||..:.|.|:::|:..:...|..:|:..|:  .:|::   :..::|:
 Frog   179 KSDTEMHNLFSRVTLDVIAKVAFGMELNSLKDDLTPLPQAISLVMNGIVETR---NPMIKYS--- 237

  Fly   228 PLAAPLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILL 292
             ||.....|::|:.|.:::. |.|...|||   ::...||...|:     ||       |..||.
 Frog   238 -LAKRGFIRKVQESIRLLRQ-TGKECIERR---QKQIQDGEEIPM-----DI-------LTQILK 285

  Fly   293 QATIDNKPLSDVDIREEVD---VFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDP 354
            .|.::    .|.|....:|   .|..||.:||.:.:|.|:..:.|:|::.:...:|:..|:|  .
 Frog   286 GAALE----EDCDPETLLDNFVTFFIAGQETTANQLSFAVMELGRNPEILQKAQKEIDEVIG--S 344

  Fly   355 DASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPE 419
            ...:....|.:|.||..|:|||:||:|..|...|.:.|::.|..:.||.|.:::...|.:.|..:
 Frog   345 RRFIEHEDLSKLHYLSQVLKETLRLYPTAPGTSRGLKEEIVIEGVRIPPNVNVMFNSYIMGRMEQ 409

  Fly   420 YFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL-LPLG 483
            .:.|||.|.|:|:   ...:..|...|.|||.||::||||.|:.::.|.:::|:::.|:. |..|
 Frog   410 NYTDPLTFNPDRF---SPGAPKPYYTYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYDFELAEG 471

  Fly   484 ADLKATYTFILSSSTGNNVGLKPRT 508
            .......|..|....|....|:|||
 Frog   472 QSFSIFDTGSLRPLDGVICRLRPRT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	124/465 (27%)
cyp46a1.1	NP_001027519.1	p450	40..491	CDD:306555	128/487 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010