Protein Alignment Cyp4d21 and cyp11a1.2

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_691817.1
• Gene: cyp11a1.2 / 563363
• ZFINID: ZDB-GENE-130911-1
• Length: 512
• Species: Danio rerio
• Alignment Length: 523
• Identity: 124/523 - (23%)
• Similarity: 209/523 - (39%)
• Gaps: 111/523 - (21%)

  Fly    45 GLQALTLRPENFIQRFGDYFNKYGKTFRLWILGECL---------------IYTKDLKYFESI-- 92
            |||..|:||.|.|.  |.:.|.....|....:|...               ||.:.:.::||:
Zfish    35 GLQDSTVRPFNEIP--GQWRNSLKSVFAFAKMGGLRNIHRIMVHNFNTFGPIYREKVGFYESVNI 97

  Fly    93 --LSSSTLLKKA--HLYRFL--------RDFLGD--GLLLSTGNKWTSRR-----KVLAPAFHFK 138
              ...:.:|.||  |..:.|        ||:...  |:||..|..|.|.|     :|::|    |
Zfish    98 IKPEDAAILFKAEGHYPKRLTIDAWTAYRDYRNRKYGVLLKDGEDWKSNRIILNKEVISP----K 158

  Fly   139 CLENFVEIMDRNSGIMV----EKLKNYADGKTCVD----LFKFVSLEALDVTTETAMGVQVNAQN 195
            ...|||.::|......|    :|::.....:...|    ||||    ||:..:....|.::.
Zfish   159 VQGNFVPLLDEVGQDFVARVNKKIERSGQNQWTTDLSHELFKF----ALESVSAVLYGERLG--- 216

  Fly   196 EPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVY------RRLQKDI---------AIM 245
                    .|...:..:|:|....   ...:|...:|::|      |.::..|         .|.
Zfish   217 --------LLLDYIDPDSQRFIDC---ITLMFKTTSPMLYLPPGLLRPIRSKIWRNHVEAWDGIF 270

  Fly   246 QDFTDKVIRE-RRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREE 309
            .. .|:.|:. .|.:.:....:|.|         .|..|.:.:||          .||..||:..
Zfish   271 NQ-ADRCIQNIYRQLRKNPEGNGKY---------TGVLASLLMLD----------KLSIEDIKAS 315

  Fly   310 VDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIK 374
            |...:..|.|||...:...|:.::|:|.:||.|..|:.:.........|...|::.|  :...:|
Zfish   316 VTELMAGGVDTTAITLLWTLYELARNPDLQEEIRAEISAARIASKGDMVQMLKMIPL--VKGTLK 378

  Fly   375 ETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTS 439
            ||:||||....|.|||.||:.|.:..||..|.:.|..|.:.||.:.||:|..:.|.||::    |
Zfish   379 ETLRLHPVAVSLQRYITEDIVIQKYHIPAGTLVQLGLYAMGRDHQVFPNPEQYLPSRWVN----S 439

  Fly   440 NTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL-LPLGADLKATYTFILSSSTGNNVG 503
            .......:.|..||:.|:|::.|..:|:..:..::.::.: .....::|:.:..||.......:.
Zfish   440 QNHYFKSLSFGFGPRQCLGRRIAETEMQLFLIHMLENFRIEKQRQMEVKSMFELILLPEKPIMLT 504

  Fly   504 LKP 506
            :||
Zfish   505 IKP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	112/494 (23%)
cyp11a1.2	XP_691817.1	cytochrome_P450	78..501	CDD:477761	110/470 (23%)