Protein Alignment Cyp4d21 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 581
• Identity: 128/581 - (22%)
• Similarity: 213/581 - (36%)
• Gaps: 136/581 - (23%)

  Fly     3 ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRF-GDYFN- 65
            :||.::.|:....|..:|.:    |.:.....|....|:||          |.|...| |..|:
Zfish    24 LLLAVSRLLWEFRWSITRDR----TCKLPLPQGSMGWPLVG----------ETFHWLFQGSSFHI 74

  Fly    66 ----KYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLL-STGNKWT 125
                |:||.|:..:||:.||.....:....||.....:......:..|..||...|: |.|:...
Zfish    75 SRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQWPQSTRIILGPNTLVNSVGDLHK 139

  Fly   126 SRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQ 190
            .:|||||..|....||.:   :.|...::..::..:......|:::.........:.....:|:.
Zfish   140 RKRKVLAKVFSRGALEAY---LTRLQDVVKSEIAKWCTETGSVEVYTAAKSLTFRIAVRVLLGLH 201

  Fly   191 VNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDI---AIMQDFTDKV 252
            :..|            .:.|: ||....:   .|.||.|........|:|.|   .|:....:|:
Zfish   202 LEEQ------------QITYL-SKTFEQL---MNNLFSLPIDTPVSGLRKGIRAREILHSAMEKI 250

  Fly   253 IRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNK-PLSDVDIREEVDVFIFA 316
            |.|:   |::.:|..                .....|.:|.:..:|. .|:..:::|.....|||
Zfish   251 IEEK---LKKQQASD----------------YCDAFDYMLSSARENDYELTMQELKETAVELIFA 296

  Fly   317 GDDTTTSGVSHALHAISRHPKVQECIYEELVS------------------VLGPDPDASVTQT-- 361
            ...||.|..:..:..:.|||.|.|....||.|                  .:..:.:|:...|
Zfish   297 AHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHCRSRCNGNAISEEGEAAEKSTSD 361

  Fly   362 --------------------------------KLLELKYLDCVIKETMRLHPPVPILGRYIPEDL 394
                                            ||.:|.|||||:||.:|..|||....|.:.:..
Zfish   362 RRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTF 426

  Fly   395 KIGEITIPGNTSILLMPYYVYRD----PEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKN 455
            ::....||...|::    |..||    .|.:.:|.:|.|:|:...:..|.:...:|:||..|.:.
Zfish   427 ELNGYQIPKGWSVM----YSIRDTHETAEAYQNPELFDPDRFCVGREESKSERFSYVPFGGGVRR 487

  Fly   456 CIGQKFANLQMKALISKVIRHYELLPLGADLKATYTF-------ILSSSTGNNVGLKPRTR 509
            |||::.|.:.:|.|.      .|||.......||.|:       |:....|.:|....||:
Zfish   488 CIGRELALIVLKTLA------VELLATADCTLATQTYPRMQTVPIVHPVNGLHVFFNYRTQ 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	109/501 (22%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	118/535 (22%)