Protein Alignment Cyp4d21 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 514
• Identity: 127/514 - (24%)
• Similarity: 208/514 - (40%)
• Gaps: 94/514 - (18%)

  Fly     3 ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFN-- 65
            :|||:|..:.||.|..|| .| .:|....:  |....|..|..|..|       :|  |..|:
Mouse    24 LLLGLAQQLWTLRWTLSR-DW-ASTLPLPK--GSMGWPFFGETLHWL-------VQ--GSRFHSS 75

  Fly    66 ---KYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLL-STGNKWTS 126
               :||..|:..:||..:|.....:...:||.....|.::...:.....||...|| :.|.....
Mouse    76 RRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQ 140

  Fly   127 RRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQV 191
            ||||||..|....||.||   .|..|.:..:::::...:..|.:::........:.....:|:|:
Mouse   141 RRKVLARVFSRSSLEQFV---PRLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQL 202

  Fly   192 NAQNEPNFPYT-KALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRE 255
            :........:| :.|     :|:            ||.|...:.:..|:|.|.......:.:
Mouse   203 DEARCTELAHTFEQL-----VEN------------LFSLPLDVPFSGLRKGIRARDQLYEHL--- 247

  Fly   256 RRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQA-TIDNKPLSDVDIREEVDVFIFAGDD 319
            ..|:.|:.:...|.:|   ||         .||.|:..| .:.::| |..:::|.....:||...
Mouse   248 DEAVAEKLQEKQTAEP---GD---------ALLLIINSARELGHEP-SVQELKELAVELLFAAFF 299

  Fly   320 TTTSGVSHALHAISRHP----KVQE----------CIYEELVSVLGPD----PDASVTQTKLLEL 366
            ||.|..:..:..:.:||    |:|:          |......|...||    ||.|:..  |..|
Mouse   300 TTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAM--LGRL 362

  Fly   367 KYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPE-----YFPDPLV 426
            :|:|||:||.:||.|||....|......::....||...|::    |..||..     |...|..
Mouse   363 RYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVM----YSIRDTHETAAVYRSPPEG 423

  Fly   427 FKPERW----MDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIR--HYEL 479
            |.|||:    .|.:.:...  ..||||..|.::|:||:.|...::.|..:::|  .:||
Mouse   424 FDPERFGVESGDARGSGGR--FHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWEL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	107/444 (24%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	114/475 (24%)