Protein Alignment Cyp4d21 and Cyp4a1

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 153/504 - (30%)
• Similarity: 257/504 - (50%)
• Gaps: 72/504 - (14%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGN-------GLQALTLRPENFI 57
            :||:.:|::..|....::||.:..|::      |..|    ..|:       .||.:....|||.
  Rat    24 VLGLLLLLVKAVQFYLQRQWLLKAFQQ------FPSPPFHWFFGHKQFQGDKELQQIMTCVENFP 82

  Fly    58 QRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAH-LYRFLRDFLGDGLLLSTG 121
            ..|..:|  :|....|      ::|..|  |.:.||..|.  .||: :||.|..::|.||||..|
  Rat    83 SAFPRWF--WGSKAYL------IVYDPD--YMKVILGRSD--PKANGVYRLLAPWIGYGLLLLNG 135

  Fly   122 NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETA 186
            ..|...|::|.||||:..|:.:|:.|..:..:|::|.:..|...:.:::|:.:||..||...:.|
  Rat   136 QPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQLAGQDSSIEIFQHISLMTLDTVMKCA 200

  Fly   187 MGVQVNAQNEPNF-PYTKALKSVVYIESKRLASVSMR----YNW-----LFPLAAPLVYRRLQKD 241
            .....:.|.:.|: .|.:|:.::..:...|:.::..:    ||:     ||..|..|.:
  Rat   201 FSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHLFNRACQLAH------ 259

  Fly   242 IAIMQDFTDKVIRERRAILERARADGTYKPLIMGD-DDIGGKAKMTLLDILLQATIDN-KPLSDV 304
                 |.||.||:.|:..|:.|           |: :.:..|.::..|||||.|.::| ..|||.
  Rat   260 -----DHTDGVIKLRKDQLQNA-----------GELEKVKKKRRLDFLDILLLARMENGDSLSDK 308

  Fly   305 DIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYL 369
            |:|.|||.|:|.|.|||.||||...:|::.||:.|:...||:.||||  ..:|:|...|.::.|.
  Rat   309 DLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLG--DGSSITWDHLDQIPYT 371

  Fly   370 DCVIKETMRLHPPVPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM 433
            ...|||.:||:||||.:.|.:...:...: .::|....:.|..|.::.:|:.:|:|.||.|.|:.
  Rat   372 TMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVWPNPEVFDPSRFA 436

  Fly   434 -DMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481
             |....|:    :::|||.|.:||||::||..:||.:::..:..:||||
  Rat   437 PDSPRHSH----SFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	146/473 (31%)
Cyp4a1	NP_787031.1	p450	52..503	CDD:278495	145/470 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348531
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850