Protein Alignment Cyp4d21 and Cyp4e1

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 196/529 - (37%)
• Similarity: 285/529 - (53%)
• Gaps: 63/529 - (11%)

  Fly     1 MWILLGIAVLIMTLVWDNSRKQWRVNTFE-----KSRIL----GPFTIPIVGNGLQALTLRPENF 56
            |||:| .|.|.:.|        :.|..||     :.|:|    ||..:|:|||..| :...|...
  Fly     1 MWIVL-CAFLALPL--------FLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQ-MGNTPTEI 55

  Fly    57 IQRFGDYFNKYGK-TFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLST 120
            :.||..::::||| .||.||.....|...:.||.|.||||.||:.|:.:|.....:||.|||.||
  Fly    56 LNRFFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTST 120

  Fly   121 GNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTET 185
            |:||...||::.|||||..|::|.|:|:.||...:::||..|||....|..:......|||..:|
  Fly   121 GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDT 185

  Fly   186 AMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTD 250
            ||||.:||....:....:|.|.:.|....|..|...|..:||..|..  |....|.:..:||||:
  Fly   186 AMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPE--YPEYSKTLKTLQDFTN 248

  Fly   251 KVIRERRAILERARADGTYKPLIMGDDDIGGKA------KMTLLDILLQATIDNKPLSDVDIREE 309
            ::|.:|..:    |..|.         ::|.||      ||..||.||.:.:|.:||:..::.||
  Fly   249 EIIAKRIEV----RKSGL---------EVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEE 300

  Fly   310 VDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPD---PDASVTQTKLLELKYLDC 371
            |..|:|.|.|||||||..|::.:||||..||.::.|...|:|..   .||  |..::..:|:||.
  Fly   301 VSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDA--TFQEISTMKHLDL 363

  Fly   372 VIKETMRLHPPVPILGRYIPEDLKI-GEITIPG---NTSILLMPYYVYRDPEYFPDPLVFKPERW 432
            .|||..||:|.||.:||:..:|..| |:|...|   |..:|::.|    :...|.||..|:|||:
  Fly   364 FIKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGY----NDRVFKDPHKFQPERF 424

  Fly   433 MDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSS 497
                ......|..|:|||:||:||||||||.|::|.::||:||::|:||...:|.:...:|  |:
  Fly   425 ----DREKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI--ST 483

  Fly   498 TGNNVGLKP 506
            |   :||:|
  Fly   484 T---LGLQP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	176/460 (38%)
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	175/460 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449039
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900