Protein Alignment Cyp4d21 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 120/519 - (23%)
• Similarity: 230/519 - (44%)
• Gaps: 93/519 - (17%)

  Fly    19 SRKQWRVNTF-----EKSRIL--GPF-TIPIVGNGLQALTLRP----------------ENFIQR 59
            ::|:|:.|..     |.|..|  .|| .||.:  .:.||:::.                |...|.
  Fly    22 TQKRWQTNVATAEAREDSEWLQAKPFEQIPRL--NMWALSMKMSMPGGKYKNMELMEMFEAMRQD 84

  Fly    60 FGDYFNKYGKTFRLWILGE-CLIYTKDLKYFESILSSS----------TLLKKAHLYRFLRDFLG 113
            :||.|      |...|:|. ..:.|.:.:.||.:..:.          |||.....||  :||..
  Fly    85 YGDIF------FMPGIMGNPPFLSTHNPQDFEVVFRNEGVWPNRPGNYTLLYHREEYR--KDFYQ 141

  Fly   114 D--GLLLSTGNKWTSRRKVLAPA-FHFKCLENFVEIMDRNSGIMVEKLKNYADGKTC------VD 169
            .  |::.:.|..|...|.|:.|. ...|.:..:.:.|.:.:...|:::....|..|.      :|
  Fly   142 GVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFID 206

  Fly   170 LFKFVSLEALDVTT-ETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYN---WLFPLA 230
            .....:||::.|.. :..:|:..|:..|     ::|||...|::...:.|:.:...   |.: :.
  Fly   207 TINRWTLESVSVVALDKQLGLLKNSNKE-----SEALKLFHYLDEFFIVSIDLEMKPSPWRY-IK 265

  Fly   231 APLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQAT 295
            .|.: :||.:.:..:|:.|...:.|....|::...:|..:|          :.:.::|:.||:
  Fly   266 TPKL-KRLMRALDGIQEVTLAYVDEAIERLDKEAKEGVVRP----------ENEQSVLEKLLK-- 317

  Fly   296 IDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQ 360
            :|.|    |.....:|: :.||.|||:|..:..|..::::|:.|..:.||::.|| |:.::..|:
  Fly   318 VDRK----VATVMAMDM-LMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKNSEFTE 376

  Fly   361 TKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPL 425
            ..:..:.||...|||:.||||.:....|.:..|..:....:|..|.:.::|.......||||...
  Fly   377 ASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQAS 441

  Fly   426 VFKPERWM------DMKTTSN----TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL 479
            .|.||||:      :.|..:|    |.|..::||..||:.|:|::...::::...:::||::.:
  Fly   442 EFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	103/446 (23%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	107/457 (23%)