Protein Alignment Cyp4d21 and Cyp312a1

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001262008.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 149/514 - (28%)
• Similarity: 280/514 - (54%)
• Gaps: 35/514 - (6%)

  Fly     2 WILLGIAVLIMTLVWDNSRKQWRVNTFEK-SRI-------LGPFTIPIVGN-GLQALTLRPENFI 57
            |:..|:.:|.::|        :.:..||: |||       ..|..:|.:|: .:.|..:.|.. :
  Fly     3 WLGFGLLLLALSL--------YLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHP-L 58

  Fly    58 QRFGDYFNKYGKTFR--LWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLST 120
            :|..:..|::....|  ||:..:..:...:.|..:::.|:..||:|.:.||...::|.:||..|.
  Fly    59 RRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSG 123

  Fly   121 GNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTET 185
            ..||:.|||::.|||::..::.||.:.::.|.|::..:..:|:....:|..:.:|...||...||
  Fly   124 FEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICET 188

  Fly   186 AMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTD 250
            |:||.|.:|:.....|..|:||::.|..|||.::..|.:::|...:.  |:|.|:.|..:..||:
  Fly   189 ALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSH--YKREQELIKTLHGFTE 251

  Fly   251 KVIRERRAILERARADGTYKPLIMGDDDIGG-KAKMTLLD-ILLQATIDNKPLSDVDIREEVDVF 313
            .:|::|   ::....|...:.....|.::.| |..:..|| :||....|.|||:..|||||||..
  Fly   252 GIIQKR---IDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTI 313

  Fly   314 IFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMR 378
            ||.|.|.|.:.::..::.::.||:.|:...||:.||.|.|....::..::.:|::|:..||||:|
  Fly   314 IFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLR 378

  Fly   379 LHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERW---MDMKTTSN 440
            ::|..|:..|....:..|.:..||..:.:::.|.|:.|..::||||:||||:||   .:.|..:.
  Fly   379 MYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEAT 443

  Fly   441 TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLG-ADLKATYTFILSSST 498
            |    :|||.:|.::|:||::|.:.:|.:::.::|::...||| ..:|....|:::..|
  Fly   444 T----FIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHT 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	134/454 (30%)
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	140/474 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449057
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900