Protein Alignment Cyp4d21 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001386630.1
• Gene: Cyp46a1 / 362782
• RGDID: 1306605
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 112/463 - (24%)
• Similarity: 210/463 - (45%)
• Gaps: 60/463 - (12%)

  Fly    60 FGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGL----LLST 120
            |.|:..|||...|:.:..:..:.....:..:..|.|:...|.:.:||.::...|:.|    |:|.
  Rat    64 FLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRAIQTVFGERLFGQGLVSE 128

  Fly   121 GN--KWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTT 183
            .:  :|..:|:|:..||....|.:.:...:..:..::|.|:..|||:|.|.:...::...:|:..
  Rat   129 CDYGRWYKQRRVMDLAFSRSSLVSLMGTFNEKAEQLMEILEAKADGQTPVSMQDMLTCATIDILA 193

  Fly   184 ETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWL--FPLAAPLVYRRLQKDIAIMQ 246
            :.|.|::.:.......|.::|:|.:       |..:|...|.|  |........|.:::.|.:::
  Rat   194 KAAFGMETSMLLGAQKPLSQAVKVM-------LEGISASRNTLAKFMPGKRKQLREIRESIRLLR 251

  Fly   247 DFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDI-REEV 310
            ......::.||..|:|            |:|        ...|||.|.....:...|.:: .:..
  Rat   252 QVGKDWVQRRREALKR------------GED--------VPADILTQILKAEEGAQDDEVLLDNF 296

  Fly   311 DVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKE 375
            ..|..||.:|:.:.::..:..:||.|::...:..|:..|:|  ....:....|..|:||..|:||
  Rat   297 VTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVG--SKRHLDYEDLGRLQYLSQVLKE 359

  Fly   376 TMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSN 440
            ::||:||.....|.:.|:..|..:.:||||.:|...|.:.|...||.|||.|.|:|:   ...:.
  Rat   360 SLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF---GPGAP 421

  Fly   441 TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYE--LLPLGADLKATYTFILSSSTGNNVG 503
            .|...|.|||.|.::||||:||.:::|.:::|:::..|  |:|                 |...|
  Rat   422 KPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP-----------------GQRFG 469

  Fly   504 LKPRTRVK 511
            |:.:..:|
  Rat   470 LQEQATLK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	105/444 (24%)
Cyp46a1	NP_001386630.1	CYP46A1-like	61..484	CDD:410706	112/463 (24%)