Protein Alignment Cyp4d21 and Cyp4e3

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 184/514 - (35%)
• Similarity: 282/514 - (54%)
• Gaps: 24/514 - (4%)

  Fly     1 MWI-LLGIAVL-IMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDY 63
            ||: :|.:.|| ::|||:...:...|....::..  ||..:||:||. ..:...|...:..|.|:
  Fly     1 MWLAVLALLVLPLITLVYFERKASQRRQLLKEFN--GPTPVPILGNA-NRIGKNPAEILSTFFDW 62

  Fly    64 FNKYGK-TFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSR 127
            :..||| .|..||.....|...:.|..|.||:|..|::|:.:|..|..:||.|||.|.|:||...
  Fly    63 WYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKH 127

  Fly   128 RKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVN 192
            ||::.|:|||..|::|.|:|:.||...:.:||..:.|.|.:|..:..:...|||..:|||||.:|
  Fly   128 RKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPIN 192

  Fly   193 AQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERR 257
            |..:.:....:|.:.:.|..:.|......|.|.:|.|...  :...||.:..:||||..:|.:|.
  Fly   193 AMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPE--FSAYQKTLKTLQDFTYDIIEKRV 255

  Fly   258 AILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTT 322
            ..|:...:...:.|.:       .:.||..||.||.:|||.:||:..:|.|||..|:|.|.||||
  Fly   256 YALQNGGSKEDHDPSL-------PRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTT 313

  Fly   323 SGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILG 387
            ||||.:::.:||||.||..:|.|...|:|.|.:.||:..::.::||||..|||..|::|.||.:|
  Fly   314 SGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIG 378

  Fly   388 RYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSG 452
            ||..:|..|....:|..|::.|....:..:...|.||..|:|||:.:.|..    |..|:|||:|
  Fly   379 RYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA----PFEYLPFSAG 439

  Fly   453 PKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSSTGNNVGLKPRTRVK 511
            |:||||||||.|::|.:||||:|.:|:||...:|.:|     .......:||.|..::|
  Fly   440 PRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVST-----DGRLNTYLGLAPDEKLK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	168/447 (38%)
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	167/446 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449021
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900