Protein Alignment Cyp4d21 and CYP27C1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001354431.1
• Gene: CYP27C1 / 339761
• HGNCID: 33480
• Length: 537
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 111/441 - (25%)
• Similarity: 196/441 - (44%)
• Gaps: 61/441 - (13%)

  Fly    66 KYGKTFRLWILGECLIYTKDLKYFESIL-SSSTLLKKAHL--YRFLRDFLG--DGLLLSTGNKWT 125
            :|||.|:.....:.::...|......:| :.....::|::  :|..||..|  .||:.:.|.:|.
Human   100 EYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYRDLRGRATGLISAEGEQWL 164

  Fly   126 S-----RRKVLAP----AFHFKCLENFVEIMDRNSGIMVEKLKNYA-DGKTCV---DLFKFVSLE 177
            .     |:::|.|    .:..:..:...:::.|     :..|::.| ||:|..   |||...|:|
Human   165 KMRSVLRQRILKPKDVAIYSGEVNQVIADLIKR-----IYLLRSQAEDGETVTNVNDLFFKYSME 224

  Fly   178 AL-DVTTETAMGVQVNAQNEPNFPYTKALKSVV-YIESKRLASVSMRYNWLFPLAAPLVYRRLQK 240
            .: .:..|:.:|...|:..:....|.:||:.:. ..::...|....|  ||.|. .|..:|...:
Human   225 GVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPR--WLRPF-IPKPWREFCR 286

  Fly   241 D----IAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPL 301
            .    ....|...|..:|:.:..::|.|...            ||         ||.....::.|
Human   287 SWDGLFKFSQIHVDNKLRDIQYQMDRGRRVS------------GG---------LLTYLFLSQAL 330

  Fly   302 SDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGP---DPDASVTQTKL 363
            :..:|...|...:.||.|||:..:|..::.::|||:||:.:|.|:|..||.   ...|.|.:..|
Human   331 TLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPL 395

  Fly   364 LELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFK 428
            :.     .::|||:||.|.:|..||...|||.||...||..|.:.|..|......|.||....|:
Human   396 VR-----ALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFR 455

  Fly   429 PERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL 479
            ||||:.............|||..|.::|||::.|.|::..::.::::|:|:
Human   456 PERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	110/439 (25%)
CYP27C1	NP_001354431.1	CYP27C1	98..530	CDD:410740	111/441 (25%)