Protein Alignment Cyp4d21 and Cyp4d2

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 230/511 - (45%)
• Similarity: 326/511 - (63%)
• Gaps: 21/511 - (4%)

  Fly     4 LLGIAVLI---MTLVWDNSRKQWRVNTFEKSRIL-GPFTIPIVGNGLQALTLRPENFIQRFGDYF 64
            ::|:.:|:   ..|:||   ..||   ...:.|| ||..:|.:||.|....|.||..:.......
  Fly     4 VVGVLLLVAFATLLLWD---FLWR---RRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQ 62

  Fly    65 NKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRK 129
            .|||:.:|:|||.:..:::.|.:..|.:|||...:.|.:||:.|..:||||||:|||.||..|||
  Fly    63 RKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRK 127

  Fly   130 VLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQ 194
            ::.|.||||.||.||||.|:.|.:|||:|::.|||.|.:::|..:.|.|||:..|||||.::|||
  Fly   128 IITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQ 192

  Fly   195 NEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRAI 259
            ..||.||.:|:..|..|..||......|.:|:|.|..|...:|..|.|.:|.|||:.:|||||..
  Fly   193 KNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRET 257

  Fly   260 LERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSG 324
            |.....:.|.:..:   :.:|.|.:|.|||:|||:|||..||||.|||||||.|:|.|.|||||.
  Fly   258 LVNNSKETTPEEEV---NFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSA 319

  Fly   325 VSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRY 389
            :|..|:.|||||:||:.:.:|:..|||.|..:.||...|.|||:::.||||::|||||||::||:
  Fly   320 ISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRW 384

  Fly   390 IPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTP---PLAYIPFSS 451
            ..||::|....||..|:..:..:.:.||||||..|..|:|||:     .::.|   |.||||||:
  Fly   385 FAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-----DADVPQIHPYAYIPFSA 444

  Fly   452 GPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSSTGNNVGLKPR 507
            ||:||||||||.|:||:.:||::||:||||||.:.:.:...:|.|:.|.::|||||
  Fly   445 GPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSANGVHLGLKPR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	210/449 (47%)
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	216/470 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449000
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	1	1.000	-	-		H82150
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28797
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	12	11.910