Protein Alignment Cyp4d21 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 163/521 - (31%)
• Similarity: 260/521 - (49%)
• Gaps: 55/521 - (10%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNKYG 68
            ||.:.:::...|....|:||.:...||.    |.|   ..:.|....|:...| |:...:..|:.
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKF----PST---PSHWLWGHDLKDREF-QQVLTWVEKFP 80

  Fly    69 KTFRLWILG---ECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFL----GDGLLLSTGNKWTS 126
            .....|:.|   ..|:|..|  |.:.:|..|. .|.:.:|:||..::    |.||||..|.||..
  Rat    81 GACLQWLSGSKTRVLLYDPD--YVKVVLGRSD-PKASGIYQFLAPWIVSGTGYGLLLLNGKKWFQ 142

  Fly   127 RRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQV 191
            ..::|.||||:..|:.:|:||..:..||::|.:...|....:::|.:|||..||...:.|...|.
  Rat   143 HWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQG 207

  Fly   192 NAQNEPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRE 255
            :.|.:.|. .||||::.:..:...|:.|.....:.::.:::.  .|..::...|..:.||.||:.
  Rat   208 SVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSD--GRLSRRACQIAHEHTDGVIKM 270

  Fly   256 RRA------ILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATI-DNKPLSDVDIREEVDVF 313
            |:|      .|::||.                |..:..|||||.|.: |.|.|||.|:|.|||.|
  Rat   271 RKAQLQNEEELQKARK----------------KRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTF 319

  Fly   314 IFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMR 378
            :|.|.|||.||:|...:|::.||:.||...||:.|:||  ...|||...|.::.|....|||.:|
  Rat   320 MFEGHDTTASGISWVFYALATHPEHQERCREEVQSILG--DGTSVTWDHLDQISYTTMCIKEALR 382

  Fly   379 LHPPVPILGRYI--PEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-DMKTTSN 440
            |:||||.:.|.:  |.....|. :||...:..::.|.::.:|.|:|:|.||.|.|:. |....|:
  Rat   383 LYPPVPSVSRELSSPVTFPDGR-SIPKGITTTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSH 446

  Fly   441 TPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYT-FILSSSTGNNVGL 504
                ||:|||.|.:||||::||..::|..::..:..:||||....:..... .:|.|..|.::.|
  Rat   447 ----AYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRL 507

  Fly   505 K 505
            |
  Rat   508 K 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	146/452 (32%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	149/465 (32%)