Protein Alignment Cyp4d21 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 186/556 - (33%)
• Similarity: 291/556 - (52%)
• Gaps: 86/556 - (15%)

  Fly     1 MWILLGIAVLIMTLVWDNSRK-------------QWRVNTFEKSRILGPF-----TIPIVGNGLQ 47
            :|:.||::...: |:|..:..             |..|:...|.:.:.|.     ..|:||:
  Rat     2 LWLWLGLSGQKL-LLWGAASAVSVAGATVLLNILQMLVSYARKWQQMRPIPSVARAYPLVGH--- 62

  Fly    48 ALTLRPEN--FIQRFGDYFNKYG--KTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFL 108
            ||.::|.|  |.|:...|..::.  ...:|||....|:.....:..|.||:||..:.|:.:|:||
  Rat    63 ALFMKPNNTEFFQQIIQYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFL 127

  Fly   109 RDFLGDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKF 173
            :.:||.|||.|||:||.:|||:|.|:|||..||:|:::|:..:.|:|.||:.:.: :...:.|..
  Rat   128 QPWLGLGLLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLEKHVN-QEAFNCFFP 191

  Fly   174 VSLEALDVTTETAMGVQVNAQNEPNFPYTKA---LKSVVYIESKRLASVSMRYNWLFPLAAPLVY 235
            ::|.|||:..|||||..:.||:..:..|.:.   :..::|...|      |.:.|.     .|.|
  Rat   192 ITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMK------MPWFWF-----DLWY 245

  Fly   236 ------RRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIG-GKA-------KMT 286
                  |..:|.:..:..||:.||.||   :...:|:         .|.|| |:.       :..
  Rat   246 LMFKEGRDHKKGLKSLHTFTNNVIAER---VNARKAE---------QDCIGAGRGPLPSKTKRKA 298

  Fly   287 LLDILLQATID--NKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSV 349
            .||:||..|.:  || ||..|||||||.|:|.|.|||.:.::.:|:.:..:|:||..:.:||..|
  Rat   299 FLDLLLSVTDEEGNK-LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDV 362

  Fly   350 LGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYV 414
            .|.. ...||...|.:|||||||||||:|:.|.||:..|.:.||.::....|...|..:::||.:
  Rat   363 FGRS-HRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAGYKISKGTEAVIIPYAL 426

  Fly   415 YRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHY-- 477
            :|||.|||||..|:|||:.. :.:....|.||:|||:||:||||||||.::.|.:::.::|.:
  Rat   427 HRDPRYFPDPEEFQPERFFP-ENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWI 490

  Fly   478 ------ELLPLGADLKATYTFILSSSTGNNVGLKPR 507
                  |.|.|..||      ||..:.|..:.||.|
  Rat   491 ESNQKREELGLAGDL------ILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	164/462 (35%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	165/471 (35%)