Protein Alignment Cyp4d21 and Cyp51

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 120/501 - (23%)
• Similarity: 206/501 - (41%)
• Gaps: 95/501 - (18%)

  Fly    39 IPIVGNGLQALTLRPENFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTL----- 98
            ||.:|:.: |....|..|::   :.:.|||..|...::|         |.|..:|.|...
  Rat    68 IPFLGHAI-AFGKSPIEFLE---NAYEKYGPVFSFTMVG---------KTFTYLLGSDAAALLFN 119

  Fly    99 -----LKKAHLY-RFLRDFLGDGLLLSTGNK-WTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVE 156
                 |....:| |......|.|:.....|. :..::|:|....:....:.:|.|:::.:   .|
  Rat   120 SKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAVFLEQKKILKSGLNIAHFKQYVSIIEKEA---KE 181

  Fly   157 KLKNYAD-GKTCVDLFKFVSLEALDVTTET--AMGVQVNAQ-NEPNFPYTKALKSVVYIESKRLA 217
            ..|::.: |:..|    |.:|..|.:.|.:  ..|.::.:| ||
  Rat   182 YFKSWGESGERNV----FEALSELIILTASHCLHGKEIRSQLNE--------------------- 221

  Fly   218 SVSMRY----------NWLFPLAAPL-VYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKP 271
            .|:..|          .||.|...|| .:||..:....:::...|.|::||...|.|
  Rat   222 KVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPA-------- 278

  Fly   272 LIMGDDDIGGKAKMTLLDILLQATI-DNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRH 335
                 :||        |..||.:|. |.:||:|.:|...:...:.||..|:::..:.....::|.
  Rat   279 -----EDI--------LQTLLDSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARD 330

  Fly   336 PKVQECIYEELVSVLGPD-PDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEI 399
            ..:|:..|.|..:|.|.| |  .:|..:|.:|..||..||||:||.||:..:.|.......:...
  Rat   331 KPLQDKCYLEQKTVCGEDLP--PLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGY 393

  Fly   400 TIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANL 464
            |||....:.:.|....|..:.:.:.|.|.|:|::.....|. ...||:||.:|...|||:.||.:
  Rat   394 TIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASG-EKFAYVPFGAGRHRCIGENFAYV 457

  Fly   465 QMKALISKVIRHYEL-LPLGADLKATYTFILSSSTGNNVGLKPRTR 509
            |:|.:.|.::|.||. |..|......||.::.:.....:..|.|::
  Rat   458 QIKTIWSTMLRLYEFDLINGYFPSVNYTTMIHTPENPVIRYKRRSK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	110/463 (24%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	112/471 (24%)