Protein Alignment Cyp4d21 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 161/517 - (31%)
• Similarity: 256/517 - (49%)
• Gaps: 54/517 - (10%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNKYG 68
            ||.:.:::...|....|:||.:...||.    |.|   ..:.|....|:...| |:...:..|:.
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKF----PST---PSHWLWGHNLKDREF-QQVLTWVEKFP 80

  Fly    69 KTFRLWILG---ECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRRKV 130
            .....|:.|   ..|:|..|  |.:.:|..|    ....|:.|..::|.||||..|.||...|::
  Rat    81 GACLQWLSGSTARVLLYDPD--YVKVVLGRS----DPKPYQSLAPWIGYGLLLLNGKKWFQHRRM 139

  Fly   131 LAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQN 195
            |.||||:..|:.:|:||..:..||::|.:...|....:::|.:|||..||...:.|...|.:.|.
  Rat   140 LTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQL 204

  Fly   196 EPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRA- 258
            :.|. .||||::.:..:...|:.|.....:.::.:::.  .|..::...|..:.||.||:.|:|
  Rat   205 DVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSD--GRLSRRACQIAHEHTDGVIKTRKAQ 267

  Fly   259 -----ILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATI-DNKPLSDVDIREEVDVFIFAG 317
                 .|::||.                |..:..|||||.|.: |.|.|||.|:|.|||.|:|.|
  Rat   268 LQNEEELQKARK----------------KRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEG 316

  Fly   318 DDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPP 382
            .|||.||:|...:|::.||:.||...||:.|:||  ...|||...|.::.|....|||.:||:.|
  Rat   317 HDTTASGISWVFYALATHPEHQERCREEVQSILG--DGTSVTWDHLDQMPYTTMCIKEALRLYSP 379

  Fly   383 VPILGRYI--PEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-DMKTTSNTPPL 444
            ||.:.|.:  |.....|. :||....:.::.|.::.:|.|:|:|.||.|.|:. |....|:
  Rat   380 VPSVSRELSSPVTFPDGR-SIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSH---- 439

  Fly   445 AYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATY-TFILSSSTGNNVGLK 505
            ||:|||.|.:||||::||..::|..::..:..:||||....:.... ..:|.|..|.::.||
  Rat   440 AYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	144/448 (32%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	147/461 (32%)