Protein Alignment Cyp4d21 and Cyp4a29

DIOPT Version :9

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001093653.1
• Gene: Cyp4a29 / 230639
• MGIID: 3717143
• Length: 509
• Species: Mus musculus
• Alignment Length: 507
• Identity: 156/507 - (30%)
• Similarity: 255/507 - (50%)
• Gaps: 41/507 - (8%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGNGLQALTLRPENFIQRFGDYF 64
            |:|:.:|:........|:||.:      |.|..|..|    :.|:.||........:|.|   |.
Mouse    24 LIGLLLLLFKAAQHYLRRQWLL------RALYQFPSPPSHWLFGHCLQFKVDEELRWILR---YL 79

  Fly    65 NKYGKTFRLWILG-ECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGNKWTSRR 128
            .|:...|..||.| ...|...|..|.:.||..:.  .||.|||||..:||.||....|::|...|
Mouse    80 EKFPGAFLHWIWGSHVFIKVCDPDYMKVILGRAD--PKASLYRFLTPWLGHGLFFLNGDEWFQHR 142

  Fly   129 KVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNA 193
            ::|.||||:..|:.:|.||..:..:|:||.:..|.....:::|..:||..||...:.|...|.:.
Mouse   143 RLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDITLEIFHPISLMMLDTIMKYAFSYQGSV 207

  Fly   194 Q-NEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERR 257
            | :..:..|.:|:..:..:.:.|:.:|.:..:.::.|.:.  .||......|..:.||:|::.|:
Mouse   208 QLDRSSQAYLQAVSDLNNLVTSRMKNVFLHNDIIYNLTSH--SRRTNSACQIAHEHTDRVVKLRK 270

  Fly   258 AILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVFIFAGDDTT 321
            |.|:..:   :.|.|       .||..:..|||||.:.:|: ..|||..:|.|||..:|.|.||.
Mouse   271 AQLQDNK---SMKKL-------RGKRCLDFLDILLLSRMDDGSSLSDKALRAEVDSLMFGGHDTP 325

  Fly   322 TSGVSHALHAISRHPKVQECIYEELVSVLGPDPDAS-VTQTKLLELKYLDCVIKETMRLHPPVPI 385
            .||:|...:|::.||..|:...||:.|:||   |.| :|...|.::.|....|||.:||:||:|.
Mouse   326 ASGISWVFYALATHPDHQQRCREEVQSLLG---DGSPITWDHLHQMPYTTMCIKEALRLYPPIPS 387

  Fly   386 LGRYI--PEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIP 448
            :||.:  |.....|. ::|...::||..|.::.:|:.:|:|.||.|.|:. |.:..::.  |::|
Mouse   388 VGRKLSTPVTFPDGR-SLPKGITVLLHFYALHHNPKVWPNPEVFDPSRFA-MNSVQHSH--AFLP 448

  Fly   449 FSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLK-ATYTFILSSSTG 499
            ||.|.:||||:..|...:|..::..:..:||||..:.:. .|...:|.|..|
Mouse   449 FSGGSRNCIGKHLAMNVLKVAVALTLLRFELLPDPSRVPIPTQQLVLKSKNG 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	143/456 (31%)
Cyp4a29	NP_001093653.1	p450	52..503	CDD:278495	147/473 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750