Protein Alignment Cyp4d21 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 140/561 - (24%)
• Similarity: 251/561 - (44%)
• Gaps: 104/561 - (18%)

  Fly     3 ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVG--NGLQALTLRPENFIQRFGDYFN 65
            ||:.||:.|....:    ..|..:.:.:..|.||..:|..|  |..|:.. :|  :|.|.||:..
 Worm     5 ILIAIALFIGVFTY----YLWIWSFWMRKGIKGPRGLPFFGIINAFQSYE-KP--WILRLGDWTK 62

  Fly    66 KYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDF-----------LGD----- 114
            :||..:......|..:...|.::...:              |::.|           .||
 Worm    63 EYGPMYGFTDGVEKTLVVSDPEFVHEV--------------FVKQFDNFYARKQNPLQGDPDKDP 113

  Fly   115 --GLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKL-KNYADGKTCVDLFKFVSL 176
              .|:.|.|::|...|.:.:|.|..|.|......::.:...|:..| |..|.||| :|:.::...
 Worm   114 RIHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKT-IDILEYYQE 177

  Fly   177 EALDVTTETAMGVQVNAQNEPNFPYTKALK-------SVVYIESKRLASVSMRYNWLF---PLAA 231
            ..:|:..:.|||...:...|.  |:...::       ::::|....:......:.|.|   |.|.
 Worm   178 FTMDIIGKIAMGQSGSMMFEN--PWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRWFFSKVPTAQ 240

  Fly   232 PLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKPL--------IMGDDDI------GGK 282
            .:.......:||:    |.:|  |:||..|:|..:.:.:|.        :..|.|.      .|.
 Worm   241 TVTSLMHTLEIAL----TKRV--EQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDETKNGF 299

  Fly   283 AKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELV 347
            |:..::.:....|.|       :|..::.||:.||.|||...:|::.:.::|||::|:.:.|| |
 Worm   300 ARSQIVKVDKHLTFD-------EIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEE-V 356

  Fly   348 SVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPIL-GRYIPEDLKIGEITIPGNTSILLMP 411
            ....|||:  ||..:|.:|||::||||||:||:|...|: .|...:...:..:.|...|::....
 Worm   357 DRECPDPE--VTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADT 419

  Fly   412 YYVYRDPEYFPDPL-VFKPERWM--DMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKV 473
            :.::.||:::.:.. .||||||.  |.:..:..   ||:||..||:.|||.:.|.::.|.|::::
 Worm   420 WTLHYDPKFWGENANEFKPERWESGDEQAVAKG---AYLPFGLGPRICIGMRLAYMEEKMLLAQI 481

  Fly   474 IRHYEL-------LPLGADLKATYTFILSSSTGNNVGLKPR 507
            ::.|.|       :||.....||     ::.|..::.||||
 Worm   482 LKKYSLETTFETHIPLKLVGIAT-----TAPTNVHLKLKPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	117/487 (24%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	117/486 (24%)