Protein Alignment Cyp4d21 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 137/561 - (24%)
• Similarity: 240/561 - (42%)
• Gaps: 118/561 - (21%)

  Fly     7 IAVLIMT-LVWDNSRKQWRVNTFEKSRIL-GPFTIPIVGNGLQAL--TLRPENFIQRFGDYFNKY 67
            |.:.|:| ..|     .|   ||.|.|.| ||:.:||.|.....|  :..|...:|:   :..:|
 Worm     6 ILISIVTYYFW-----HW---TFWKRRGLPGPWGVPIFGKAGAMLEDSFPPGYTLQK---WTKEY 59

  Fly    68 GKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLG------DG---------LL 117
            ||.:.         :|:.::.. .::|...|:::. |.:...:|.|      .|         ::
 Worm    60 GKIYG---------FTEGMQKV-MVISDPDLVQEI-LVKQYDNFYGRKHNPVQGDPDKDKDIHIV 113

  Fly   118 LSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVT 182
            .:.|.:|...|.:.||||....::..:..|:.::..:::||:..::....|::..|......||.
 Worm   114 GAQGFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLFYQEYTFDVI 178

  Fly   183 TETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQ-------- 239
            :..||| |.::|...| |..|.:|.  :.|..|...      |:|....|.....|:
 Worm   179 SRVAMG-QPDSQMFKN-PLLKDVKG--FFEHNRWQI------WMFSGGFPFAVSFLKWLFIKVGK 233

  Fly   240 ----KDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQA------ 294
                ..|.:.:..||.|: .|.|..|..:..|. :|         |:| ...:|:.|.|
 Worm   234 FGAGPFIVVQKSVTDAVM-SRIAQREADKKHGV-EP---------GEA-ADYIDMFLNARAEVEH 286

  Fly   295 ------------TIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELV 347
                        :.:|:.|:..:|..:..||:.||.|||...:|:..:.::.:||:|..:.:|:.
 Worm   287 FGESNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVD 351

  Fly   348 SVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPIL-GRYIPEDLKIGEITIPGNTSILLMP 411
            ...   |:..:|..:|.:|||:|.||||::||.|..... .|....:..|||..:.....:::..
 Worm   352 KEC---PNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQIVEAGVDVMIDT 413

  Fly   412 YYVYRDPEYF-PDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIR 475
            :.::.|...: .|...||||||    .:..||..||:.|.:||:.|:|.:||.|:.|.|:|.:::
 Worm   414 WTLHHDKNVWGNDVEEFKPERW----DSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILK 474

  Fly   476 HYEL-------LPLGADLKATYTFILSSSTGNN--VGLKPR 507
            .|..       ||:....:||       :...|  :.||||
 Worm   475 KYTFETNAKTQLPIKLVGRAT-------ARPENLFLSLKPR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	114/489 (23%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	114/488 (23%)