Protein Alignment Cyp4d21 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 104/552 - (18%)
• Similarity: 212/552 - (38%)
• Gaps: 147/552 - (26%)

  Fly     5 LGIAVLIMTLV--------WDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQ-ALTLRPENFIQRF 60
            :|:.|.::.::        |.:|  .|:     :..|.||..:|.:|:... |...:|..||
 Worm     1 MGVIVCLVAIIGVVAGYFKWIHS--YWK-----RRGIEGPVGLPFIGSFYDLADREKPRGFI--- 55

  Fly    61 GDYFNKYGKTFRLWILGECLIYTKDLKYFESIL-----SSSTLLKKAHLYRFLRDFLGD------ 114
               .||:.|.|           .|...|:|.::     |...:|::..:.:|      |
 Worm    56 ---INKWTKMF-----------GKVFGYYEGVIPVLVVSDLDMLQEMFIKKF------DCFYARK 100

  Fly   115 ------------------GLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNY 161
                              .|..:.|.:|...|.:.:|||..|.|:...|.|:.:...||:.:...
 Worm   101 TTNLIHGNLECSQEEPRVNLFAARGARWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHMSKQ 165

  Fly   162 ADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQ-NEPNFPYTKALKSVVYIESKRLASVSMRYNW 225
            .:|: ..::.::......||.:..|||...:.| |.......|.    :::...|:      |.|
 Worm   166 VNGE-AFNIHEYYQEFTYDVISRLAMGQTYSEQFNNEGVDIVKK----IFLRKNRV------YPW 219

  Fly   226 LFPLAAPLVYRRLQK-----------DIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDI 279
            ...:..|.....::.           |:..:..|.:..:.:|.    :.|||...:.:....:|
 Worm   220 YLAVMFPGFENTIKNTFFNHEAVRGGDVGKLLKFCETAVHDRL----KERADNVEQGIENPHND- 279

  Fly   280 GGKAKMTLLDILLQATID------------NKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAI 332
                   .:|:.|....|            .|.::..|:.....||:.||.|||.:.:::|.:.:
 Worm   280 -------FIDMFLDYYTDTNIEDNAFGIKVEKKVTSEDVIGACFVFLLAGFDTTANTLAYASYLL 337

  Fly   333 SRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIG 397
            ::||:....:.:|:..:...:   .::...:.:|:|:|.||:|.:|::|..     :.....:..
 Worm   338 AKHPQEMRKVQDEIDRICTSE---HISYDDIGKLRYMDAVIREALRMYPVA-----WFACSRECV 394

  Fly   398 EITIPGNTSILLMPYYV--------------YRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIP 448
            :.|..||       ||:              |.:..:..:...|.||||::.....|   :::||
 Worm   395 QATTLGN-------YYIEKGVRIEADVRALHYSEEIWGKNANEFVPERWLESSPRHN---MSWIP 449

  Fly   449 FSSGPKNCIGQKFANLQMKALISKVIRHYELL 480
            |.:||:.|:|.:....:.|..::.::|.:.:|
 Worm   450 FGAGPRQCVGMRLGLSEAKTALAHLLRRFSIL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	88/480 (18%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	87/478 (18%)