Protein Alignment Cyp4d21 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 136/513 - (26%)
• Similarity: 227/513 - (44%)
• Gaps: 104/513 - (20%)

  Fly    23 WRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNKYGKTFRLWILGECLIYTKDLK 87
            |..:.:::..|.||...||:|:.|:.|:.....::| ..::..:|||.:.:         |:.|.
 Worm    21 WTWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQ-LKEWTKQYGKVYGI---------TEGLS 75

  Fly    88 YFESILSSSTLLKKAHLYRF-------LRDFLGD-------GLLLSTGNKWTSRRKVLAPAFHFK 138
            . ..::|...|:::..:.::       |....||       .|..|.|::|...|.:.:|.|...
 Worm    76 R-TLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRVNLFSSQGHRWKRLRTISSPTFSNN 139

  Fly   139 CLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQ--NEPNFPY 201
            .|......::..:..::..::.:.||...:||..|.....|||....||| |.::|  ..|..||
 Worm   140 SLRKLKTTVEECAVELLRHIEQHTDGGQPIDLLDFYQEFTLDVIGRIAMG-QTDSQMFKNPLLPY 203

  Fly   202 TKALKSVVYIESKR--LASVSMRYNWLFPLAAPLVYR--RLQKDIAIMQDFTDKVIRE-RRAILE 261
            .:|    |:.|.::  ..|.|:. .|:.|:...:::.  .:.|:.|:      .|||. ..|:.:
 Worm   204 VRA----VFGEPRKGLFLSGSLA-PWIGPILRMVMFSLPNIVKNPAV------HVIRHTSNAVEQ 257

  Fly   262 RARADGTYKPLIMGDDDIG---GKAKMTLLDILLQATIDNKPLSDVDIREEVD------------ 311
            |.:       |.|.|:..|   |:.: ..:|:.|.|..|     ||::....|
 Worm   258 RVK-------LRMADEKAGIDPGEPQ-DFIDLFLDAKSD-----DVELENNEDFTKAGVKVTRQL 309

  Fly   312 ----------VFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLEL 366
                      ||:.||.|||...:|::...::.|||||:.:.||:..... ||:  ||..:|.:|
 Worm   310 TTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRECA-DPE--VTFDQLSKL 371

  Fly   367 KYLDCVIKETMRLHPPVPILG-----RYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYF-PDPL 425
            ||::||||||:|::|    ||     |......|||...|...|:||...:.::.|...: .|..
 Worm   372 KYMECVIKETLRMYP----LGALANSRCCMRATKIGNYEIDEGTNILCDTWTLHSDKSIWGEDAE 432

  Fly   426 VFKPERWMDMKTTSNTPPL----AYIPFSSGPKNCIGQKFANLQMKALISKVIRHYEL 479
            .||||||     .|.....    .||||..||:.|||.:.|.::.|.|:|.::|.|.|
 Worm   433 EFKPERW-----ESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	125/468 (27%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	126/470 (27%)