Protein Alignment Cyp4d21 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 122/540 - (22%)
• Similarity: 247/540 - (45%)
• Gaps: 64/540 - (11%)

  Fly     1 MWILLGIAVLIMTLVWDNSRKQWRVNTFEKSR-ILGPFTIPIVGNGLQALTL-RPENFI-----Q 58
            |..::.:.||..|:.   ...:| ::|:.:.| |.||..:|.:||......: :|..::     |
 Worm     1 MGAIIVLVVLFATIA---GYFKW-IHTYWRRRGISGPEGLPFIGNYYDLADVNKPRGYLIHKWTQ 61

  Fly    59 RFGDYFNKYGKTFRLWILGEC-LIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGD---GLLLS 119
            :||..|..|.....:.::.:. ::....||.|::..:..:   ..|::..|.....:   .|..|
 Worm    62 KFGKVFGYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKS---TNHIHGNLECSKSEPRINLFTS 123

  Fly   120 TGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTE 184
            .|.:|...|.:.:|.|..|.|:...::|:.::..||:.:..:.|||. .::..:......||.:.
 Worm   124 RGARWKRLRALASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGKP-FNIHAYFQEFTYDVISR 187

  Fly   185 TAMGVQVNAQ--NEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQD 247
            .||| |.|::  |.......|:    :::.:.|:  :...:..|||....||.|......|:...
 Worm   188 LAMG-QPNSELFNNSGVEIVKS----IFMRTHRV--LPWYFTVLFPQFEHLVKRMFYNHAAVQGG 245

  Fly   248 FTDKVI-------------RERRAILERARADGTYKPLIMG--DDDIGGKAKMTLLDILLQATID 297
            ..:|::             ||..|.|....|:..:..:.:.  .:.:.        ||...:|::
 Worm   246 DIEKLLLICKKTVESRIQEREENAKLGFENAENDFIDMFLNYYSEQVE--------DIEFGSTVE 302

  Fly   298 NKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTK 362
            .|..:: |:.....||:.||.|||.:.:::|.:.:::||:..:...||:.:|:|.:   :|:...
 Worm   303 KKVTAE-DVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSE---NVSYDD 363

  Fly   363 LLELKYLDCVIKETMRLHPPVPI-LGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPL- 425
            :.:|||||.|::|::||:|.... ..|...:...:|:|.|.....|......::|..|.:.:..
 Worm   364 MTKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENAD 428

  Fly   426 VFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATY 490
            .|.||||::   .|:...:::|||.:||:.|:|.:....:.|..::.::|.|:|: .|.:.:...
 Worm   429 DFVPERWLE---PSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRYDLV-AGVETEKEL 489

  Fly   491 TFILSSSTGN---NVGLKPR 507
            ..:..::|..   .:.||||
 Worm   490 NILGCTTTSPEAVTLYLKPR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	99/459 (22%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	103/464 (22%)