Protein Alignment Cyp4d21 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 532
• Identity: 159/532 - (29%)
• Similarity: 261/532 - (49%)
• Gaps: 68/532 - (12%)

  Fly     1 MW---ILLGIAVL-IMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGNGLQALTLRPENFI 57
            :|   ::|.:.|| :::|::   |:|      :.:|.|..|..|    :.|:.|:         |
Mouse    15 LWASVVILMVTVLKLLSLLF---RRQ------KLARALDSFPGPPKHWLFGHALE---------I 61

  Fly    58 QRFG------DYFNKYGKTFRLWILGECL----IYTKDLKYFESILSSSTLLKKAHLYRFLRDFL 112
            |:.|      .:..::.....|| ||:.:    ||..|  |.:::.|... .|.|::|.|...::
Mouse    62 QKTGGLDKVVTWTEQFPYAHPLW-LGQFIVFLNIYEPD--YAKAVYSRGD-PKAAYVYDFFLQWI 122

  Fly   113 GDGLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLE 177
            |.|||:..|.||...||:|.|.||:..|:.:|.|...::.:|::|.:..|......|:|..|...
Mouse   123 GKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHM 187

  Fly   178 ALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYN-----WLFPLAAPLVYRR 237
            |||...:...|...:..:..:..|..|:..:..:..:|:.  |.:|:     ||.|..     ||
Mouse   188 ALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRID--SFQYHNDFIYWLTPHG-----RR 245

  Fly   238 LQKDIAIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNK-PL 301
            ..:...|..|.||.|||:|:|.|:..:.          ...:..:..:..|||||.|..::. .|
Mouse   246 FLRACQIAHDHTDHVIRQRKAALQDEKE----------QKKLQERRHLDFLDILLGARDESGIKL 300

  Fly   302 SDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLEL 366
            ||.|:|.|||.|:|.|.||||||:|..|:.::.:|..|:...||:..:|| |.| |.....|.::
Mouse   301 SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILG-DRD-SFQWDDLAQM 363

  Fly   367 KYLDCVIKETMRLHPPVPILGRYIPEDLK-IGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPE 430
            .||...:||..||:||||.:.|.:.:.:. :...::|..:.|.|..|.::|:...:|||.||.|.
Mouse   364 TYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPL 428

  Fly   431 RWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATY-TFIL 494
            |:.....|.. .|.|::|||:||:|||||:||..:||.:.:..:..:|..|..:.:.... ..||
Mouse   429 RFSPENMTGR-HPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLIL 492

  Fly   495 SSSTGNNVGLKP 506
            .|..|.::.|||
Mouse   493 RSKNGIHLYLKP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	140/445 (31%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	140/457 (31%)