Protein Alignment Cyp4d21 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 495
• Identity: 148/495 - (29%)
• Similarity: 256/495 - (51%)
• Gaps: 54/495 - (10%)

  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGN-------GLQALTLRPENFI 57
            :||:.:|::..|.....:||.:..|::      |..|    ..|:       .||.:....|||.
Mouse    24 VLGLLLLLVKAVQFYLHRQWLLKAFQQ------FPSPPFHWFFGHEKFKGDQELQEIVSCIENFP 82

  Fly    58 QRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAH-LYRFLRDFLGDGLLLSTG 121
            ..|..:|  :|....|      .:|..|  |.:.||..|.  .||: .||.|..::|.||||..|
Mouse    83 SAFPRWF--WGSKAYL------TVYDPD--YMKVILGRSD--PKANGAYRLLAPWIGYGLLLLNG 135

  Fly   122 NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETA 186
            ..|...|::|.||||:..|:.:|:.|..:..:|::|.:..||..:.:::|:.:||..||...:.|
Mouse   136 QPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCA 200

  Fly   187 MGVQVNAQNEPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIA-IMQDFT 249
            ...:.:.|.:.|: .|.:|:..:..:...|:.::..:.:.::.|::   ..||.|... :..|.|
Mouse   201 FSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSS---NGRLAKQACQLAHDHT 262

  Fly   250 DKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVF 313
            |.||:.|:   ::.:.:|..       :.|..|.::..|||||.|.::| ..:||.|:|.|||.|
Mouse   263 DGVIKLRK---DQLQDEGEL-------EKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTF 317

  Fly   314 IFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMR 378
            :|.|.|||.||||...:|::.||..|:...||:.|:||  ..:|:|...|.::.|....|||.:|
Mouse   318 MFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLG--DGSSITWDHLDQIPYTTMCIKEALR 380

  Fly   379 LHPPVPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-DMKTTSNT 441
            |:||||.:.|.:...:...: .::|....:.|..|.::.:|:.:|:|.||.|.|:. |....|:
Mouse   381 LYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH- 444

  Fly   442 PPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481
               :::|||.|.:||||::||..::|.:::..:..:||||
Mouse   445 ---SFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	131/420 (31%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	138/442 (31%)