Protein Alignment Cyp4d21 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 505
• Identity: 139/505 - (27%)
• Similarity: 249/505 - (49%)
• Gaps: 74/505 - (14%)

  Fly     2 WILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPIVGNGLQALTLRPENFIQRFGDYFNK 66
            |:||..:::::.|...:|.     ..|:|..|.||..:|.:|    .:....:.|.:.......|
Mouse    12 WMLLATSLVLLYLYGTHSH-----GIFKKLGIPGPKPLPFLG----TILAYQKGFWECDIQCHKK 67

  Fly    67 YGKTFRLWILGECLIYTKDLKYFESIL-----SSST---------LLKKAHLYRFLRDFLGDGLL 117
            |||.:.|:...:.::...|....:::|     |:.|         :||||             :.
Mouse    68 YGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKA-------------IS 119

  Fly   118 LSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLK-NYADGK--TCVDLFKFVSLEAL 179
            :|...:|...|.:|:|.|....|:....|:::.:.::|..:: ...:||  :..|:|...|   :
Mouse   120 ISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYS---M 181

  Fly   180 DVTTETAMGVQVNAQNEPNFPYTKALKSVVYIE--SKRLASVSMRYNWLFPLAAPLVYRRLQKDI 242
            ||.|.|:.||.:::.|.|..|:.:.:|.::..:  .....||:     |||...| |:..|...:
Mouse   182 DVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVT-----LFPFLTP-VFDALNVSL 240

  Fly   243 ---AIMQDFTDKVIR---ERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPL 301
               .::..||..|.|   .|....|:.|.|  :..|::...:...|.             .:|.|
Mouse   241 FPRDVISFFTTSVERMKENRMKEKEKQRVD--FLQLMINSQNYKTKE-------------SHKAL 290

  Fly   302 SDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLEL 366
            |||:|..:..:|||||.:||:|.:|.||:.::.||.||:.:.:|:.:.| |: .|..|...||::
Mouse   291 SDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL-PN-KAPATYDTLLQM 353

  Fly   367 KYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPER 431
            :|||.|:.||:||:|....|.|....|::|..:.||..|.:::..:.:::||:|:|:|..|:|||
Mouse   354 EYLDMVVNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPER 418

  Fly   432 WMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481
            : ..|...:..|..|:||.|||:||||.:||.:.||..:.:|::::.:.|
Mouse   419 F-SKKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	124/439 (28%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	126/441 (29%)